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Infusion rate and plasma volume expansion of dextran and albumin in the septic guinea pig.

Bark, Björn LU and Grände, Per-Olof LU (2014) In Acta Anaesthesiologica Scandinavica 58(1). p.44-51
Abstract
Intravenous fluid treatment of hypovolaemia in states of increased capillary permeability, e.g. sepsis, is often accompanied by adverse oedema formation. A challenge is therefore to achieve and maintain normovolaemia using as little plasma volume substitution as possible to minimise interstitial oedema. In the present study, we evaluated the importance of infusion rate for the plasma volume expanding effects of 6% dextran 70 and 5% human albumin in a guinea pig sepsis model.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Anaesthesiologica Scandinavica
volume
58
issue
1
pages
44 - 51
publisher
Wiley-Blackwell
external identifiers
  • wos:000328156800007
  • pmid:24251847
  • scopus:84890521836
ISSN
0001-5172
DOI
10.1111/aas.12228
language
English
LU publication?
yes
id
7ee4576a-98f2-4c1f-aa65-80ac81d662c9 (old id 4179191)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24251847?dopt=Abstract
date added to LUP
2013-12-03 17:36:57
date last changed
2017-07-23 03:05:31
@article{7ee4576a-98f2-4c1f-aa65-80ac81d662c9,
  abstract     = {Intravenous fluid treatment of hypovolaemia in states of increased capillary permeability, e.g. sepsis, is often accompanied by adverse oedema formation. A challenge is therefore to achieve and maintain normovolaemia using as little plasma volume substitution as possible to minimise interstitial oedema. In the present study, we evaluated the importance of infusion rate for the plasma volume expanding effects of 6% dextran 70 and 5% human albumin in a guinea pig sepsis model.},
  author       = {Bark, Björn and Grände, Per-Olof},
  issn         = {0001-5172},
  language     = {eng},
  number       = {1},
  pages        = {44--51},
  publisher    = {Wiley-Blackwell},
  series       = {Acta Anaesthesiologica Scandinavica},
  title        = {Infusion rate and plasma volume expansion of dextran and albumin in the septic guinea pig.},
  url          = {http://dx.doi.org/10.1111/aas.12228},
  volume       = {58},
  year         = {2014},
}