Expression of microRNAs is essential for arterial myogenic tone and pressure-induced activation of the PI3-kinase/Akt pathway.
(2014) In Cardiovascular Research 101(2). p.288-296- Abstract
- The myogenic response is the intrinsic ability of small arteries to constrict in response to increased intraluminal pressure. Although microRNAs have been shown to play a role in vascular smooth muscle function, their importance in the regulation of the myogenic response is not known. In this study, we investigate the role of microRNAs in the regulation of myogenic tone by using smooth muscle-specific and tamoxifen-inducible deletion of the endonuclease Dicer in mice.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4179332
- author
- Bhattachariya, Anirban LU ; Dahan, Diana LU ; Turczynska, Karolina LU ; Swärd, Karl LU ; Hellstrand, Per LU and Albinsson, Sebastian LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Cardiovascular Research
- volume
- 101
- issue
- 2
- pages
- 288 - 296
- publisher
- Oxford University Press
- external identifiers
-
- pmid:24233972
- wos:000330835300013
- scopus:84893099457
- pmid:24233972
- ISSN
- 1755-3245
- DOI
- 10.1093/cvr/cvt253
- language
- English
- LU publication?
- yes
- id
- 4c59570a-4b3a-43f6-ad59-f6dac993c4eb (old id 4179332)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24233972?dopt=Abstract
- date added to LUP
- 2016-04-01 10:57:54
- date last changed
- 2022-04-28 03:14:10
@article{4c59570a-4b3a-43f6-ad59-f6dac993c4eb, abstract = {{The myogenic response is the intrinsic ability of small arteries to constrict in response to increased intraluminal pressure. Although microRNAs have been shown to play a role in vascular smooth muscle function, their importance in the regulation of the myogenic response is not known. In this study, we investigate the role of microRNAs in the regulation of myogenic tone by using smooth muscle-specific and tamoxifen-inducible deletion of the endonuclease Dicer in mice.}}, author = {{Bhattachariya, Anirban and Dahan, Diana and Turczynska, Karolina and Swärd, Karl and Hellstrand, Per and Albinsson, Sebastian}}, issn = {{1755-3245}}, language = {{eng}}, number = {{2}}, pages = {{288--296}}, publisher = {{Oxford University Press}}, series = {{Cardiovascular Research}}, title = {{Expression of microRNAs is essential for arterial myogenic tone and pressure-induced activation of the PI3-kinase/Akt pathway.}}, url = {{https://lup.lub.lu.se/search/files/2270589/4391254.pdf}}, doi = {{10.1093/cvr/cvt253}}, volume = {{101}}, year = {{2014}}, }