Synthesis of Formylsilanes through Oxidative Cleavage of α-Silyl Glycols.
(2013) In Journal of Organic Chemistry 78(23). p.12268-12273- Abstract
- A convenient method for the synthesis and isolation of highly reactive formylsilanes by oxidative cleavage of α-silyl glycols is presented. The mild conditions provide an entry to acid- and heat-sensitive members of this theoretically intriguing class of compounds. The utility of the method is demonstrated through the isolation and subsequent diastereoselective derivatization of t-BuMe2- and t-BuPh2-formylsilanes, previously not reported in isolated form.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4179901
- author
- von Wachenfeldt, Henrik LU and Strand, Daniel LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Organic Chemistry
- volume
- 78
- issue
- 23
- pages
- 12268 - 12273
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- wos:000328231600072
- pmid:24180618
- scopus:84890190815
- pmid:24180618
- ISSN
- 1520-6904
- DOI
- 10.1021/jo402123j
- language
- English
- LU publication?
- yes
- id
- 253c1505-be09-4f1c-bba3-5513b53acc59 (old id 4179901)
- date added to LUP
- 2016-04-01 11:05:11
- date last changed
- 2022-04-20 08:56:59
@article{253c1505-be09-4f1c-bba3-5513b53acc59, abstract = {{A convenient method for the synthesis and isolation of highly reactive formylsilanes by oxidative cleavage of α-silyl glycols is presented. The mild conditions provide an entry to acid- and heat-sensitive members of this theoretically intriguing class of compounds. The utility of the method is demonstrated through the isolation and subsequent diastereoselective derivatization of t-BuMe2- and t-BuPh2-formylsilanes, previously not reported in isolated form.}}, author = {{von Wachenfeldt, Henrik and Strand, Daniel}}, issn = {{1520-6904}}, language = {{eng}}, number = {{23}}, pages = {{12268--12273}}, publisher = {{The American Chemical Society (ACS)}}, series = {{Journal of Organic Chemistry}}, title = {{Synthesis of Formylsilanes through Oxidative Cleavage of α-Silyl Glycols.}}, url = {{http://dx.doi.org/10.1021/jo402123j}}, doi = {{10.1021/jo402123j}}, volume = {{78}}, year = {{2013}}, }