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An auxin-driven polarized transport model for phyllotaxis

Jönsson, Henrik LU ; Heisler, M ; Shapiro, BE ; Meyerowitz, EM and Mjolsness, E (2006) In Proceedings of the National Academy of Sciences 103(5). p.1633-1638
Abstract
Recent studies show that plant organ positioning may be mediated by localized concentrations of the plant hormone auxin. Auxin patterning in the shoot apical meristem is in turn brought about by the subcellular polar distribution of the putative auxin efflux mediator, PIN1. However, the question of what signals determine PIN1 polarization and how this gives rise to regular patterns of auxin concentration remains unknown. Here we address these questions by using mathematical modeling combined with confocal imaging. We propose a model that is based on the assumption that auxin influences the polarization of its own efflux within the meristem epidermis. We show that such a model is sufficient to create regular spatial patterns of auxin... (More)
Recent studies show that plant organ positioning may be mediated by localized concentrations of the plant hormone auxin. Auxin patterning in the shoot apical meristem is in turn brought about by the subcellular polar distribution of the putative auxin efflux mediator, PIN1. However, the question of what signals determine PIN1 polarization and how this gives rise to regular patterns of auxin concentration remains unknown. Here we address these questions by using mathematical modeling combined with confocal imaging. We propose a model that is based on the assumption that auxin influences the polarization of its own efflux within the meristem epidermis. We show that such a model is sufficient to create regular spatial patterns of auxin concentration on systems with static and dynamic cellular connectivities, the latter governed by a mechanical model. We also optimize parameter values for the PIN1 dynamics by using a detailed auxin transport model, for which parameter values are taken from experimental estimates, together with a template consisting of cell and wall compartments as well as PIN1 concentrations quantitatively extracted from confocal data. The model shows how polarized transport can drive the formation of regular patterns. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
meristern, formation, pattern, dynamical model, Arabidopsis thaliana, computable plant
in
Proceedings of the National Academy of Sciences
volume
103
issue
5
pages
1633 - 1638
publisher
National Acad Sciences
external identifiers
  • wos:000235094300085
  • scopus:31944449689
ISSN
1091-6490
DOI
10.1073/pnas.0509839103
language
English
LU publication?
yes
id
5dc86821-58b1-4e78-b6c4-667451113dd3 (old id 418037)
date added to LUP
2016-04-01 12:34:35
date last changed
2021-10-06 05:34:38
@article{5dc86821-58b1-4e78-b6c4-667451113dd3,
  abstract     = {Recent studies show that plant organ positioning may be mediated by localized concentrations of the plant hormone auxin. Auxin patterning in the shoot apical meristem is in turn brought about by the subcellular polar distribution of the putative auxin efflux mediator, PIN1. However, the question of what signals determine PIN1 polarization and how this gives rise to regular patterns of auxin concentration remains unknown. Here we address these questions by using mathematical modeling combined with confocal imaging. We propose a model that is based on the assumption that auxin influences the polarization of its own efflux within the meristem epidermis. We show that such a model is sufficient to create regular spatial patterns of auxin concentration on systems with static and dynamic cellular connectivities, the latter governed by a mechanical model. We also optimize parameter values for the PIN1 dynamics by using a detailed auxin transport model, for which parameter values are taken from experimental estimates, together with a template consisting of cell and wall compartments as well as PIN1 concentrations quantitatively extracted from confocal data. The model shows how polarized transport can drive the formation of regular patterns.},
  author       = {Jönsson, Henrik and Heisler, M and Shapiro, BE and Meyerowitz, EM and Mjolsness, E},
  issn         = {1091-6490},
  language     = {eng},
  number       = {5},
  pages        = {1633--1638},
  publisher    = {National Acad Sciences},
  series       = {Proceedings of the National Academy of Sciences},
  title        = {An auxin-driven polarized transport model for phyllotaxis},
  url          = {http://dx.doi.org/10.1073/pnas.0509839103},
  doi          = {10.1073/pnas.0509839103},
  volume       = {103},
  year         = {2006},
}