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Abnormal oral vascular network pattern geometry: A new clinical sign of Down syndrome

Latini, G ; Bianciardi, G ; Parrini, S ; Laurini, Ricardo LU and De Felice, C (2006) In Journal of Pediatrics 148(1). p.132-137
Abstract
Down syndrome is a leading genetic cause of mental retardation. Here, we show high fractal dimensions and Lempel-Ziv complexity and lower minimum path fractal dimension (P <= .0006) for the oral vascular networks of patients (n = 14) and their unaffected parents. This newly recognized sign may provide a useful phenotypical marker for identifying couples potentially at risk for offspring with Down syndrome.
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Pediatrics
volume
148
issue
1
pages
132 - 137
publisher
Academic Press
external identifiers
  • wos:000234954900029
  • pmid:16423614
  • scopus:30744443845
  • pmid:16423614
ISSN
1097-6833
DOI
10.1016/j.jpeds.2005.08.049
language
English
LU publication?
yes
id
ee60f289-94f3-488a-9751-61a2a351c270 (old id 419393)
date added to LUP
2016-04-01 11:39:37
date last changed
2021-02-17 04:27:36
@article{ee60f289-94f3-488a-9751-61a2a351c270,
  abstract     = {Down syndrome is a leading genetic cause of mental retardation. Here, we show high fractal dimensions and Lempel-Ziv complexity and lower minimum path fractal dimension (P &lt;= .0006) for the oral vascular networks of patients (n = 14) and their unaffected parents. This newly recognized sign may provide a useful phenotypical marker for identifying couples potentially at risk for offspring with Down syndrome.},
  author       = {Latini, G and Bianciardi, G and Parrini, S and Laurini, Ricardo and De Felice, C},
  issn         = {1097-6833},
  language     = {eng},
  number       = {1},
  pages        = {132--137},
  publisher    = {Academic Press},
  series       = {Journal of Pediatrics},
  title        = {Abnormal oral vascular network pattern geometry: A new clinical sign of Down syndrome},
  url          = {http://dx.doi.org/10.1016/j.jpeds.2005.08.049},
  doi          = {10.1016/j.jpeds.2005.08.049},
  volume       = {148},
  year         = {2006},
}