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Abnormal oral vascular network pattern geometry: A new clinical sign of Down syndrome

Latini, G ; Bianciardi, G ; Parrini, S ; Laurini, Ricardo LU and De Felice, C (2006) In Journal of Pediatrics 148(1). p.132-137
Abstract
Down syndrome is a leading genetic cause of mental retardation. Here, we show high fractal dimensions and Lempel-Ziv complexity and lower minimum path fractal dimension (P <= .0006) for the oral vascular networks of patients (n = 14) and their unaffected parents. This newly recognized sign may provide a useful phenotypical marker for identifying couples potentially at risk for offspring with Down syndrome.
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Pediatrics
volume
148
issue
1
pages
132 - 137
publisher
Academic Press
external identifiers
  • wos:000234954900029
  • pmid:16423614
  • scopus:30744443845
  • pmid:16423614
ISSN
1097-6833
DOI
10.1016/j.jpeds.2005.08.049
language
English
LU publication?
yes
id
ee60f289-94f3-488a-9751-61a2a351c270 (old id 419393)
date added to LUP
2016-04-01 11:39:37
date last changed
2025-10-14 09:57:12
@article{ee60f289-94f3-488a-9751-61a2a351c270,
  abstract     = {{Down syndrome is a leading genetic cause of mental retardation. Here, we show high fractal dimensions and Lempel-Ziv complexity and lower minimum path fractal dimension (P &lt;= .0006) for the oral vascular networks of patients (n = 14) and their unaffected parents. This newly recognized sign may provide a useful phenotypical marker for identifying couples potentially at risk for offspring with Down syndrome.}},
  author       = {{Latini, G and Bianciardi, G and Parrini, S and Laurini, Ricardo and De Felice, C}},
  issn         = {{1097-6833}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{132--137}},
  publisher    = {{Academic Press}},
  series       = {{Journal of Pediatrics}},
  title        = {{Abnormal oral vascular network pattern geometry: A new clinical sign of Down syndrome}},
  url          = {{http://dx.doi.org/10.1016/j.jpeds.2005.08.049}},
  doi          = {{10.1016/j.jpeds.2005.08.049}},
  volume       = {{148}},
  year         = {{2006}},
}