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Optical microscope based on multispectral imaging applied to Plasmodium diagnosis

Zoueu, Jérémie T. ; Loum, Georges L. ; Cisse Haba, T. ; Brydegaard, Mikkel LU and Menan, Hervé (2008) In Journal of Applied Sciences 8(15). p.2711-2717
Abstract

We have adapted an optical transmission microscope to multispectral imaging in order to diagnose Plasmodium falciparum without using fluorescent labels for parasites as is the case for the thick and thin blood smears. We show how a set of monochromatic Light Emitting Diodes (LEDs) has provided an efficient contrast and spatial resolution to identify the parasites inside the erythrocytes. The obtained images have been processed using MATLAB software to improve the contrast. This method is a promising alternative for malaria diagnosis.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Erythrocyte, Falciparum, Imaging process, Malaria diagnosis, Optical instrument, Spectroscopy
in
Journal of Applied Sciences
volume
8
issue
15
pages
7 pages
publisher
Asian Network for Scientific Information
external identifiers
  • scopus:58149521155
ISSN
1812-5654
DOI
10.3923/jas.2008.2711.2717
language
English
LU publication?
yes
id
41a73ca3-d36a-4b4f-97af-b25dcb0b6565
date added to LUP
2025-12-01 12:17:48
date last changed
2025-12-02 14:22:21
@article{41a73ca3-d36a-4b4f-97af-b25dcb0b6565,
  abstract     = {{<p>We have adapted an optical transmission microscope to multispectral imaging in order to diagnose Plasmodium falciparum without using fluorescent labels for parasites as is the case for the thick and thin blood smears. We show how a set of monochromatic Light Emitting Diodes (LEDs) has provided an efficient contrast and spatial resolution to identify the parasites inside the erythrocytes. The obtained images have been processed using MATLAB software to improve the contrast. This method is a promising alternative for malaria diagnosis.</p>}},
  author       = {{Zoueu, Jérémie T. and Loum, Georges L. and Cisse Haba, T. and Brydegaard, Mikkel and Menan, Hervé}},
  issn         = {{1812-5654}},
  keywords     = {{Erythrocyte; Falciparum; Imaging process; Malaria diagnosis; Optical instrument; Spectroscopy}},
  language     = {{eng}},
  number       = {{15}},
  pages        = {{2711--2717}},
  publisher    = {{Asian Network for Scientific Information}},
  series       = {{Journal of Applied Sciences}},
  title        = {{Optical microscope based on multispectral imaging applied to Plasmodium diagnosis}},
  url          = {{http://dx.doi.org/10.3923/jas.2008.2711.2717}},
  doi          = {{10.3923/jas.2008.2711.2717}},
  volume       = {{8}},
  year         = {{2008}},
}