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Cubosomes for ruthenium complex delivery: formulation and characterization

Mangiapia, Gaetano ; Vaccaro, Mauro ; D'Errico, Gerardino ; Frielinghaus, Henrich ; Radulescu, Aurel ; Pipich, Vitaliy ; Carnerup, Anna LU and Paduano, Luigi (2011) In Soft Matter 7(22). p.10577-10580
Abstract
An amphiphilic ruthenium-based molecule (DOPURu) with potential antineoplastic activity has been synthesized, and its aggregation behavior in the presence of phospholipids has been investigated. A very rich variety of aggregates has been found, spanning from vesicles to cubic bicontinuous phases. Cubosomes here presented represent one of the first systems with potential use for medical therapy.
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author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Soft Matter
volume
7
issue
22
pages
10577 - 10580
publisher
Royal Society of Chemistry
external identifiers
  • wos:000296388300011
  • scopus:84255183363
ISSN
1744-6848
DOI
10.1039/c1sm06323e
language
English
LU publication?
yes
id
41dbcc0e-c411-45bc-a360-b30e691eb769 (old id 2253650)
date added to LUP
2016-04-01 14:18:25
date last changed
2022-01-27 23:56:28
@article{41dbcc0e-c411-45bc-a360-b30e691eb769,
  abstract     = {{An amphiphilic ruthenium-based molecule (DOPURu) with potential antineoplastic activity has been synthesized, and its aggregation behavior in the presence of phospholipids has been investigated. A very rich variety of aggregates has been found, spanning from vesicles to cubic bicontinuous phases. Cubosomes here presented represent one of the first systems with potential use for medical therapy.}},
  author       = {{Mangiapia, Gaetano and Vaccaro, Mauro and D'Errico, Gerardino and Frielinghaus, Henrich and Radulescu, Aurel and Pipich, Vitaliy and Carnerup, Anna and Paduano, Luigi}},
  issn         = {{1744-6848}},
  language     = {{eng}},
  number       = {{22}},
  pages        = {{10577--10580}},
  publisher    = {{Royal Society of Chemistry}},
  series       = {{Soft Matter}},
  title        = {{Cubosomes for ruthenium complex delivery: formulation and characterization}},
  url          = {{http://dx.doi.org/10.1039/c1sm06323e}},
  doi          = {{10.1039/c1sm06323e}},
  volume       = {{7}},
  year         = {{2011}},
}