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Prehospital Coagulation Monitoring of Resuscitation With Point-of-Care Devices.

Schött, Ulf LU (2014) In Shock 41(Dec 20). p.26-29
Abstract
A variety of Point-Of-Care monitors for the measurement of hematocrit, hemoglobin, blood gas with electrolytes and lactate can be used also in the prehospital setting for optimizing and individualizing trauma resucitation. Point-Of-Care coagulation testing with activated prothrombin test, prothrombin test and activated coagulation/clotting time tests are available for prehospital use. Although robust, battery driven and easy to handle, many devices lack documentation for use in prehospital care. Some of the devices correspond poorly to corresponding laboratory analyses in acute trauma coagulopathy and at lower hematocrits. In trauma, viscoelastic tests like rotational thromboelastometry and thromboelastography can rapidly detect acute... (More)
A variety of Point-Of-Care monitors for the measurement of hematocrit, hemoglobin, blood gas with electrolytes and lactate can be used also in the prehospital setting for optimizing and individualizing trauma resucitation. Point-Of-Care coagulation testing with activated prothrombin test, prothrombin test and activated coagulation/clotting time tests are available for prehospital use. Although robust, battery driven and easy to handle, many devices lack documentation for use in prehospital care. Some of the devices correspond poorly to corresponding laboratory analyses in acute trauma coagulopathy and at lower hematocrits. In trauma, viscoelastic tests like rotational thromboelastometry and thromboelastography can rapidly detect acute trauma coagulopathy and give an overall dynamic picture of the hemostatic system and the interaction between its different components: coagulation activation, fibrin polymerization, fibrin platelet interactions within the clot and fibrinolysis. Rotational thromboelastometry is shock resistant and has the potential to be used outside the hospital setting to guide individualized coagulation factor and blood component therapies. Sonoclot® and Rheorox® are two small size viscoelastic instruments with one channel options, but with less documentation. The Point-Of-Care market for coagulation tests are quickly expanding and new devices are introduced all the time. Still they should be better adopted to prehospital conditions, be small, robust, battery charged, rapid, use small sample volumes and whole blood. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Shock
volume
41
issue
Dec 20
pages
26 - 29
publisher
BioMedical Press
external identifiers
  • pmid:24365883
  • wos:000336965100005
  • scopus:84899587137
ISSN
1540-0514
DOI
10.1097/SHK.0000000000000108
language
English
LU publication?
yes
id
d71a25f1-4c64-4eaf-95f5-2f2e2f16c8fe (old id 4223037)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24365883?dopt=Abstract
date added to LUP
2014-01-06 11:55:26
date last changed
2017-11-12 03:02:22
@article{d71a25f1-4c64-4eaf-95f5-2f2e2f16c8fe,
  abstract     = {A variety of Point-Of-Care monitors for the measurement of hematocrit, hemoglobin, blood gas with electrolytes and lactate can be used also in the prehospital setting for optimizing and individualizing trauma resucitation. Point-Of-Care coagulation testing with activated prothrombin test, prothrombin test and activated coagulation/clotting time tests are available for prehospital use. Although robust, battery driven and easy to handle, many devices lack documentation for use in prehospital care. Some of the devices correspond poorly to corresponding laboratory analyses in acute trauma coagulopathy and at lower hematocrits. In trauma, viscoelastic tests like rotational thromboelastometry and thromboelastography can rapidly detect acute trauma coagulopathy and give an overall dynamic picture of the hemostatic system and the interaction between its different components: coagulation activation, fibrin polymerization, fibrin platelet interactions within the clot and fibrinolysis. Rotational thromboelastometry is shock resistant and has the potential to be used outside the hospital setting to guide individualized coagulation factor and blood component therapies. Sonoclot® and Rheorox® are two small size viscoelastic instruments with one channel options, but with less documentation. The Point-Of-Care market for coagulation tests are quickly expanding and new devices are introduced all the time. Still they should be better adopted to prehospital conditions, be small, robust, battery charged, rapid, use small sample volumes and whole blood.},
  author       = {Schött, Ulf},
  issn         = {1540-0514},
  language     = {eng},
  number       = {Dec 20},
  pages        = {26--29},
  publisher    = {BioMedical Press},
  series       = {Shock},
  title        = {Prehospital Coagulation Monitoring of Resuscitation With Point-of-Care Devices.},
  url          = {http://dx.doi.org/10.1097/SHK.0000000000000108},
  volume       = {41},
  year         = {2014},
}