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Circulating glycosaminoglycan species in septic shock.

Nelson, Axel LU ; Berkestedt, Ingrid LU and Bodelsson, Mikael LU (2014) In Acta Anaesthesiologica Scandinavica 58(1). p.36-43
Abstract
Glycosaminoglycans (GAGs) are negatively charged polysaccharides present, e.g., on the luminal face of the blood vessels as heparan sulphate (HS) and hyaluronic acid (HA), in the interstitium as HA, and in neutrofils and plasma as chondroitin sulphate (CS) and HA. Total plasma levels of GAG are increased in human septic shock, but the origin and pathophysiological implications are unclear. In order to determine the source of circulating GAG in sepsis, we compared plasma levels of HS, HA, CS and keratan sulphate (KS) in patients with septic shock and controls.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Anaesthesiologica Scandinavica
volume
58
issue
1
pages
36 - 43
publisher
Wiley-Blackwell
external identifiers
  • wos:000328156800006
  • pmid:24341693
  • scopus:84890567173
ISSN
0001-5172
DOI
10.1111/aas.12223
language
English
LU publication?
yes
id
2f7fcfe6-18e4-48aa-805d-921caf58b5dc (old id 4223618)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24341693?dopt=Abstract
date added to LUP
2014-01-05 18:43:21
date last changed
2017-08-13 03:19:30
@article{2f7fcfe6-18e4-48aa-805d-921caf58b5dc,
  abstract     = {Glycosaminoglycans (GAGs) are negatively charged polysaccharides present, e.g., on the luminal face of the blood vessels as heparan sulphate (HS) and hyaluronic acid (HA), in the interstitium as HA, and in neutrofils and plasma as chondroitin sulphate (CS) and HA. Total plasma levels of GAG are increased in human septic shock, but the origin and pathophysiological implications are unclear. In order to determine the source of circulating GAG in sepsis, we compared plasma levels of HS, HA, CS and keratan sulphate (KS) in patients with septic shock and controls.},
  author       = {Nelson, Axel and Berkestedt, Ingrid and Bodelsson, Mikael},
  issn         = {0001-5172},
  language     = {eng},
  number       = {1},
  pages        = {36--43},
  publisher    = {Wiley-Blackwell},
  series       = {Acta Anaesthesiologica Scandinavica},
  title        = {Circulating glycosaminoglycan species in septic shock.},
  url          = {http://dx.doi.org/10.1111/aas.12223},
  volume       = {58},
  year         = {2014},
}