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Patch Testing with Formaldehyde 2.0% in Parallel with 1.0% by the Swedish Contact Dermatitis Research Group.

Isaksson, Marléne LU ; Bråred-Christensson, Johanna; Engfeldt, Malin LU ; Lindberg, Magnus; Matura, Mihaly; Möller, Halvor LU ; Morgardt-Ryberg, Kristina LU ; Stenberg, Berndt; Svedman, Cecilia LU and Bruze, Magnus LU (2014) In Acta Dermato-Venereologica 94(4). p.408-410
Abstract
In a multicentre study consecutively patch-tested dermatitis patients were tested simultaneously with 1.0% and 2.0% (w/v) formaldehyde in aqua applied with a micropipette (15 µl) to the filter paper disc in Finn Chambers (0.30 mg/cm2 and 0.60 mg/cm2, respectively). A total of 2,122 dermatitis patients were patch-tested. In all, 77 (3.6%) patients reacted positively to formaldehyde; 37 reacted only to 2.0%, 35 reacted to both concentrations and 5 patients reacted only to 1.0%. Significantly more patients were thus diagnosed with contact allergy to formaldehyde with 2.0% compared to 1.0% (p < 0.001) without causing more irritant reactions. The detected number of isolated allergic reactions to the 2 formaldehyde-releasers in the Swedish... (More)
In a multicentre study consecutively patch-tested dermatitis patients were tested simultaneously with 1.0% and 2.0% (w/v) formaldehyde in aqua applied with a micropipette (15 µl) to the filter paper disc in Finn Chambers (0.30 mg/cm2 and 0.60 mg/cm2, respectively). A total of 2,122 dermatitis patients were patch-tested. In all, 77 (3.6%) patients reacted positively to formaldehyde; 37 reacted only to 2.0%, 35 reacted to both concentrations and 5 patients reacted only to 1.0%. Significantly more patients were thus diagnosed with contact allergy to formaldehyde with 2.0% compared to 1.0% (p < 0.001) without causing more irritant reactions. The detected number of isolated allergic reactions to the 2 formaldehyde-releasers in the Swedish baseline series and not to formaldehyde itself raises the question whether quaternium-15 1.0% and diazolidinyl urea 2.0% should be present in the Swedish baseline series. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Dermato-Venereologica
volume
94
issue
4
pages
408 - 410
publisher
Medical Journals Limited
external identifiers
  • pmid:24337098
  • wos:000339416100007
  • scopus:84902794289
ISSN
1651-2057
DOI
10.2340/00015555-1748
language
English
LU publication?
yes
id
a3319cea-9e67-4c64-82cd-17b1ce36df53 (old id 4223684)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24337098?dopt=Abstract
date added to LUP
2014-01-04 18:19:36
date last changed
2017-01-01 03:49:46
@article{a3319cea-9e67-4c64-82cd-17b1ce36df53,
  abstract     = {In a multicentre study consecutively patch-tested dermatitis patients were tested simultaneously with 1.0% and 2.0% (w/v) formaldehyde in aqua applied with a micropipette (15 µl) to the filter paper disc in Finn Chambers (0.30 mg/cm2 and 0.60 mg/cm2, respectively). A total of 2,122 dermatitis patients were patch-tested. In all, 77 (3.6%) patients reacted positively to formaldehyde; 37 reacted only to 2.0%, 35 reacted to both concentrations and 5 patients reacted only to 1.0%. Significantly more patients were thus diagnosed with contact allergy to formaldehyde with 2.0% compared to 1.0% (p &lt; 0.001) without causing more irritant reactions. The detected number of isolated allergic reactions to the 2 formaldehyde-releasers in the Swedish baseline series and not to formaldehyde itself raises the question whether quaternium-15 1.0% and diazolidinyl urea 2.0% should be present in the Swedish baseline series.},
  author       = {Isaksson, Marléne and Bråred-Christensson, Johanna and Engfeldt, Malin and Lindberg, Magnus and Matura, Mihaly and Möller, Halvor and Morgardt-Ryberg, Kristina and Stenberg, Berndt and Svedman, Cecilia and Bruze, Magnus},
  issn         = {1651-2057},
  language     = {eng},
  number       = {4},
  pages        = {408--410},
  publisher    = {Medical Journals Limited},
  series       = {Acta Dermato-Venereologica},
  title        = {Patch Testing with Formaldehyde 2.0% in Parallel with 1.0% by the Swedish Contact Dermatitis Research Group.},
  url          = {http://dx.doi.org/10.2340/00015555-1748},
  volume       = {94},
  year         = {2014},
}