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Differential localization and characterization of functional calcitonin gene-related peptide receptors in human subcutaneous arteries.

Edvinsson, Lars LU ; Ahnstedt, Hilda LU ; Larsen, R and Sheykhzade, M (2014) In Acta Physiologica 210(4). p.811-822
Abstract
Calcitonin gene-related peptide (CGRP) and its receptor are widely distributed within the circulation and the mechanism behind its vasodilation not only differs from one animal species to another but is also dependent on the type and size of vessel. The present study examines the nature of CGRP-induced vasodilation, characteristics of the CGRP receptor antagonist telcagepant and localization of the key components calcitonin receptor-like receptor (CLR) and receptor activity modifying protein 1 (RAMP1) of the CGRP receptor in human subcutaneous arteries.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Physiologica
volume
210
issue
4
pages
811 - 822
publisher
Wiley-Blackwell
external identifiers
  • pmid:24330354
  • wos:000332757600013
  • scopus:84896044767
ISSN
1748-1708
DOI
10.1111/apha.12213
language
English
LU publication?
yes
id
36b64d44-e59e-4e2d-82a0-512872462b67 (old id 4223894)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24330354?dopt=Abstract
date added to LUP
2014-01-04 12:38:36
date last changed
2017-06-18 03:26:06
@article{36b64d44-e59e-4e2d-82a0-512872462b67,
  abstract     = {Calcitonin gene-related peptide (CGRP) and its receptor are widely distributed within the circulation and the mechanism behind its vasodilation not only differs from one animal species to another but is also dependent on the type and size of vessel. The present study examines the nature of CGRP-induced vasodilation, characteristics of the CGRP receptor antagonist telcagepant and localization of the key components calcitonin receptor-like receptor (CLR) and receptor activity modifying protein 1 (RAMP1) of the CGRP receptor in human subcutaneous arteries.},
  author       = {Edvinsson, Lars and Ahnstedt, Hilda and Larsen, R and Sheykhzade, M},
  issn         = {1748-1708},
  language     = {eng},
  number       = {4},
  pages        = {811--822},
  publisher    = {Wiley-Blackwell},
  series       = {Acta Physiologica},
  title        = {Differential localization and characterization of functional calcitonin gene-related peptide receptors in human subcutaneous arteries.},
  url          = {http://dx.doi.org/10.1111/apha.12213},
  volume       = {210},
  year         = {2014},
}