Chromosome-scale genome assembly of the brown anole (Anolis sagrei), an emerging model species
(2022) In Communications Biology 5(1).- Abstract
Rapid technological improvements are democratizing access to high quality, chromosome-scale genome assemblies. No longer the domain of only the most highly studied model organisms, now non-traditional and emerging model species can be genome-enabled using a combination of sequencing technologies and assembly software. Consequently, old ideas built on sparse sampling across the tree of life have recently been amended in the face of genomic data drawn from a growing number of high-quality reference genomes. Arguably the most valuable are those long-studied species for which much is already known about their biology; what many term emerging model species. Here, we report a highly complete chromosome-scale genome assembly for the brown... (More)
Rapid technological improvements are democratizing access to high quality, chromosome-scale genome assemblies. No longer the domain of only the most highly studied model organisms, now non-traditional and emerging model species can be genome-enabled using a combination of sequencing technologies and assembly software. Consequently, old ideas built on sparse sampling across the tree of life have recently been amended in the face of genomic data drawn from a growing number of high-quality reference genomes. Arguably the most valuable are those long-studied species for which much is already known about their biology; what many term emerging model species. Here, we report a highly complete chromosome-scale genome assembly for the brown anole, Anolis sagrei – a lizard species widely studied across a variety of disciplines and for which a high-quality reference genome was long overdue. This assembly exceeds the vast majority of existing reptile and snake genomes in contiguity (N50 = 253.6 Mb) and annotation completeness. Through the analysis of this genome and population resequence data, we examine the history of repetitive element accumulation, identify the X chromosome, and propose a hypothesis for the evolutionary history of fusions between autosomes and the X that led to the sex chromosomes of A. sagrei.
(Less)
- author
- organization
- publishing date
- 2022
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Communications Biology
- volume
- 5
- issue
- 1
- article number
- 1126
- publisher
- Nature Publishing Group
- external identifiers
-
- pmid:36284162
- scopus:85140575664
- ISSN
- 2399-3642
- DOI
- 10.1038/s42003-022-04074-5
- language
- English
- LU publication?
- yes
- id
- 425cfb7f-08fa-4152-b4dc-961f94d82dc8
- date added to LUP
- 2022-12-06 13:26:34
- date last changed
- 2024-04-18 16:01:14
@article{425cfb7f-08fa-4152-b4dc-961f94d82dc8,
abstract = {{<p>Rapid technological improvements are democratizing access to high quality, chromosome-scale genome assemblies. No longer the domain of only the most highly studied model organisms, now non-traditional and emerging model species can be genome-enabled using a combination of sequencing technologies and assembly software. Consequently, old ideas built on sparse sampling across the tree of life have recently been amended in the face of genomic data drawn from a growing number of high-quality reference genomes. Arguably the most valuable are those long-studied species for which much is already known about their biology; what many term emerging model species. Here, we report a highly complete chromosome-scale genome assembly for the brown anole, Anolis sagrei – a lizard species widely studied across a variety of disciplines and for which a high-quality reference genome was long overdue. This assembly exceeds the vast majority of existing reptile and snake genomes in contiguity (N50 = 253.6 Mb) and annotation completeness. Through the analysis of this genome and population resequence data, we examine the history of repetitive element accumulation, identify the X chromosome, and propose a hypothesis for the evolutionary history of fusions between autosomes and the X that led to the sex chromosomes of A. sagrei.</p>}},
author = {{Geneva, Anthony J. and Park, Sungdae and Bock, Dan G. and de Mello, Pietro L.H. and Sarigol, Fatih and Tollis, Marc and Donihue, Colin M. and Reynolds, R. Graham and Feiner, Nathalie and Rasys, Ashley M. and Lauderdale, James D. and Minchey, Sergio G. and Alcala, Aaron J. and Infante, Carlos R. and Kolbe, Jason J. and Schluter, Dolph and Menke, Douglas B. and Losos, Jonathan B.}},
issn = {{2399-3642}},
language = {{eng}},
number = {{1}},
publisher = {{Nature Publishing Group}},
series = {{Communications Biology}},
title = {{Chromosome-scale genome assembly of the brown anole (Anolis sagrei), an emerging model species}},
url = {{http://dx.doi.org/10.1038/s42003-022-04074-5}},
doi = {{10.1038/s42003-022-04074-5}},
volume = {{5}},
year = {{2022}},
}