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Plasma autoantibodies against apolipoprotein B-100 peptide 210 in subclinical atherosclerosis.

McLeod, Olga ; Silveira, Angela ; Nordin Fredrikson, Gunilla LU ; Gertow, Karl ; Baldassarre, Damiano ; Veglia, Fabrizio ; Sennblad, Bengt ; Strawbridge, Rona J ; Larsson, Malin and Leander, Karin , et al. (2014) In Atherosclerosis 232(1). p.242-248
Abstract
Experimental studies have suggested that autoimmunity is involved in atherosclerosis and provided evidence that both protective and pro-atherogenic immune responses exist. This concept has received support from small clinical studies implicating autoantibodies directed against apolipoprotein B-100 (apoB-100) in human atherosclerosis. We examined circulating autoantibodies directed against native and malondialdehyde (MDA)-modified epitope p210 of apoB-100 (IgG-p210nat and IgM-p210MDA) in relation to early atherosclerosis in a large, European longitudinal cohort study of healthy high-risk individuals.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Atherosclerosis
volume
232
issue
1
pages
242 - 248
publisher
Elsevier
external identifiers
  • wos:000329209100037
  • pmid:24401246
  • scopus:84891720846
  • pmid:24401246
ISSN
1879-1484
DOI
10.1016/j.atherosclerosis.2013.11.041
language
English
LU publication?
yes
id
e742d3ff-a870-405e-a2e5-c41068513e6f (old id 4291889)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24401246?dopt=Abstract
date added to LUP
2016-04-01 09:59:54
date last changed
2022-04-27 17:34:40
@article{e742d3ff-a870-405e-a2e5-c41068513e6f,
  abstract     = {{Experimental studies have suggested that autoimmunity is involved in atherosclerosis and provided evidence that both protective and pro-atherogenic immune responses exist. This concept has received support from small clinical studies implicating autoantibodies directed against apolipoprotein B-100 (apoB-100) in human atherosclerosis. We examined circulating autoantibodies directed against native and malondialdehyde (MDA)-modified epitope p210 of apoB-100 (IgG-p210nat and IgM-p210MDA) in relation to early atherosclerosis in a large, European longitudinal cohort study of healthy high-risk individuals.}},
  author       = {{McLeod, Olga and Silveira, Angela and Nordin Fredrikson, Gunilla and Gertow, Karl and Baldassarre, Damiano and Veglia, Fabrizio and Sennblad, Bengt and Strawbridge, Rona J and Larsson, Malin and Leander, Karin and Gigante, Bruna and Kauhanen, Jussi and Rauramaa, Rainer and Smit, Andries J and Mannarino, Elmo and Giral, Philippe and Humphries, Steve E and Tremoli, Elena and de Faire, Ulf and Ohrvik, John and Nilsson, Jan and Hamsten, Anders}},
  issn         = {{1879-1484}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{242--248}},
  publisher    = {{Elsevier}},
  series       = {{Atherosclerosis}},
  title        = {{Plasma autoantibodies against apolipoprotein B-100 peptide 210 in subclinical atherosclerosis.}},
  url          = {{http://dx.doi.org/10.1016/j.atherosclerosis.2013.11.041}},
  doi          = {{10.1016/j.atherosclerosis.2013.11.041}},
  volume       = {{232}},
  year         = {{2014}},
}