Toll-Like Receptor 3 Signalling Up-Regulates Expression of the HIV Co-Receptor G-Protein Coupled Receptor 15 on Human CD4(+) T Cells.
(2014) In PLoS ONE 9(2).- Abstract
- Many HIV-2 and SIV isolates, as well as some HIV-1 strains, can use the orphan 7-transmembrane receptor GPR15 as co-receptor for efficient entry into host cells. GPR15 is expressed on central memory and effector memory CD4(+) T cells in healthy individuals and a subset of these cells is susceptible to HIV-1 and SIV infection. However, it has not been determined whether GPR15 expression is altered in the context of HIV-1 infection.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4334314
- author
- Kiene, Miriam ; Rethi, Bence ; Jansson, Marianne LU ; Dillon, Stephanie ; Lee, Eric ; Lantto, Rebecka ; Wilson, Cara ; Pöhlmann, Stefan and Chiodi, Francesca
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- PLoS ONE
- volume
- 9
- issue
- 2
- article number
- e88195
- publisher
- Public Library of Science (PLoS)
- external identifiers
-
- pmid:24558379
- wos:000331706700025
- scopus:84895891496
- pmid:24558379
- ISSN
- 1932-6203
- DOI
- 10.1371/journal.pone.0088195
- language
- English
- LU publication?
- yes
- id
- 769984f9-ef12-4b00-a4c3-af787bdefc8d (old id 4334314)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24558379?dopt=Abstract
- date added to LUP
- 2016-04-01 13:52:18
- date last changed
- 2022-03-21 20:59:03
@article{769984f9-ef12-4b00-a4c3-af787bdefc8d, abstract = {{Many HIV-2 and SIV isolates, as well as some HIV-1 strains, can use the orphan 7-transmembrane receptor GPR15 as co-receptor for efficient entry into host cells. GPR15 is expressed on central memory and effector memory CD4(+) T cells in healthy individuals and a subset of these cells is susceptible to HIV-1 and SIV infection. However, it has not been determined whether GPR15 expression is altered in the context of HIV-1 infection.}}, author = {{Kiene, Miriam and Rethi, Bence and Jansson, Marianne and Dillon, Stephanie and Lee, Eric and Lantto, Rebecka and Wilson, Cara and Pöhlmann, Stefan and Chiodi, Francesca}}, issn = {{1932-6203}}, language = {{eng}}, number = {{2}}, publisher = {{Public Library of Science (PLoS)}}, series = {{PLoS ONE}}, title = {{Toll-Like Receptor 3 Signalling Up-Regulates Expression of the HIV Co-Receptor G-Protein Coupled Receptor 15 on Human CD4(+) T Cells.}}, url = {{https://lup.lub.lu.se/search/files/3637645/4611029.pdf}}, doi = {{10.1371/journal.pone.0088195}}, volume = {{9}}, year = {{2014}}, }