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Skin sensitizers differentially regulate signaling pathways in MUTZ-3 cells in relation to their individual potency.

Albrekt, Ann-Sofie LU ; Johansson, Henrik LU ; Börjesson, Anna; Borrebaeck, Carl LU and Lindstedt, Malin LU (2014) In BMC Pharmacology 15(1).
Abstract
Due to the recent European legislations posing a ban of animal tests for safety assessment within the cosmetic industry, development of in vitro alternatives for assessment of skin sensitization is highly prioritized. To date, proposed in vitro assays are mainly based on single biomarkers, which so far have not been able to classify and stratify chemicals into subgroups, related to risk or potency.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
BMC Pharmacology
volume
15
issue
1
publisher
BioMed Central
external identifiers
  • pmid:24517095
  • wos:000333272700001
  • scopus:84899943716
ISSN
2050-6511
DOI
10.1186/2050-6511-15-5
language
English
LU publication?
yes
id
eb7f172c-138b-4f72-8b05-46df0d048d6c (old id 4334876)
date added to LUP
2014-03-06 14:24:56
date last changed
2017-09-17 04:13:29
@article{eb7f172c-138b-4f72-8b05-46df0d048d6c,
  abstract     = {Due to the recent European legislations posing a ban of animal tests for safety assessment within the cosmetic industry, development of in vitro alternatives for assessment of skin sensitization is highly prioritized. To date, proposed in vitro assays are mainly based on single biomarkers, which so far have not been able to classify and stratify chemicals into subgroups, related to risk or potency.},
  articleno    = {5},
  author       = {Albrekt, Ann-Sofie and Johansson, Henrik and Börjesson, Anna and Borrebaeck, Carl and Lindstedt, Malin},
  issn         = {2050-6511},
  language     = {eng},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {BMC Pharmacology},
  title        = {Skin sensitizers differentially regulate signaling pathways in MUTZ-3 cells in relation to their individual potency.},
  url          = {http://dx.doi.org/10.1186/2050-6511-15-5},
  volume       = {15},
  year         = {2014},
}