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Light in and sound out: emerging translational strategies for photoacoustic imaging.

Zackrisson, Sophia LU ; van de Ven, S M W Y and Gambhir, S S (2014) In Cancer Research 74(4). p.979-1004
Abstract
Photoacoustic imaging (PAI) has the potential for real-time molecular imaging at high resolution and deep inside the tissue, using nonionizing radiation and not necessarily depending on exogenous imaging agents, making this technique very promising for a range of clinical applications. The fact that PAI systems can be made portable and compatible with existing imaging technologies favors clinical translation even more. The breadth of clinical applications in which photoacoustics could play a valuable role include: noninvasive imaging of the breast, sentinel lymph nodes, skin, thyroid, eye, prostate (transrectal), and ovaries (transvaginal); minimally invasive endoscopic imaging of gastrointestinal tract, bladder, and circulating tumor... (More)
Photoacoustic imaging (PAI) has the potential for real-time molecular imaging at high resolution and deep inside the tissue, using nonionizing radiation and not necessarily depending on exogenous imaging agents, making this technique very promising for a range of clinical applications. The fact that PAI systems can be made portable and compatible with existing imaging technologies favors clinical translation even more. The breadth of clinical applications in which photoacoustics could play a valuable role include: noninvasive imaging of the breast, sentinel lymph nodes, skin, thyroid, eye, prostate (transrectal), and ovaries (transvaginal); minimally invasive endoscopic imaging of gastrointestinal tract, bladder, and circulating tumor cells (in vivo flow cytometry); and intraoperative imaging for assessment of tumor margins and (lymph node) metastases. In this review, we describe the basics of PAI and its recent advances in biomedical research, followed by a discussion of strategies for clinical translation of the technique. Cancer Res; 74(4); 979-1004. ©2014 AACR. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Cancer Research
volume
74
issue
4
pages
979 - 1004
publisher
American Association for Cancer Research Inc.
external identifiers
  • pmid:24514041
  • wos:000331876600001
  • scopus:84894256424
ISSN
1538-7445
DOI
10.1158/0008-5472.CAN-13-2387
language
English
LU publication?
yes
id
7fa5504a-27dd-47e7-921c-4cca533d1559 (old id 4334948)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24514041?dopt=Abstract
date added to LUP
2014-03-06 11:42:27
date last changed
2017-11-12 03:15:22
@article{7fa5504a-27dd-47e7-921c-4cca533d1559,
  abstract     = {Photoacoustic imaging (PAI) has the potential for real-time molecular imaging at high resolution and deep inside the tissue, using nonionizing radiation and not necessarily depending on exogenous imaging agents, making this technique very promising for a range of clinical applications. The fact that PAI systems can be made portable and compatible with existing imaging technologies favors clinical translation even more. The breadth of clinical applications in which photoacoustics could play a valuable role include: noninvasive imaging of the breast, sentinel lymph nodes, skin, thyroid, eye, prostate (transrectal), and ovaries (transvaginal); minimally invasive endoscopic imaging of gastrointestinal tract, bladder, and circulating tumor cells (in vivo flow cytometry); and intraoperative imaging for assessment of tumor margins and (lymph node) metastases. In this review, we describe the basics of PAI and its recent advances in biomedical research, followed by a discussion of strategies for clinical translation of the technique. Cancer Res; 74(4); 979-1004. ©2014 AACR.},
  author       = {Zackrisson, Sophia and van de Ven, S M W Y and Gambhir, S S},
  issn         = {1538-7445},
  language     = {eng},
  number       = {4},
  pages        = {979--1004},
  publisher    = {American Association for Cancer Research Inc.},
  series       = {Cancer Research},
  title        = {Light in and sound out: emerging translational strategies for photoacoustic imaging.},
  url          = {http://dx.doi.org/10.1158/0008-5472.CAN-13-2387},
  volume       = {74},
  year         = {2014},
}