Advanced

International consensus criteria for the diagnosis of Raynaud's phenomenon.

Maverakis, Emanual; Patel, Forum; Kronenberg, Daniel G; Chung, Lorinda; Fiorentino, David; Allanore, Yannick; Guiducci, Serena; Hesselstrand, Roger LU ; Hummers, Laura K and Duong, Chris, et al. (2014) In Journal of Autoimmunity 48-49(Jan 31). p.60-65
Abstract
Vasoconstriction accompanied by changes in skin color is a normal physiologic response to cold. The distinction between this normal physiology and Raynaud's phenomenon (RP) has yet to be well characterized. In anticipation of the 9th International Congress on Autoimmunity, a panel of 12 RP experts from 9 different institutes and four different countries were assembled for a Delphi exercise to establish new diagnostic criteria for RP. Relevant investigators with highly cited manuscripts in Raynaud's-related research were identified using the Web of Science and invited to participate. Surveys at each stage were administered to participants via the on-line SurveyMonkey software tool. The participants evaluated the level of appropriateness of... (More)
Vasoconstriction accompanied by changes in skin color is a normal physiologic response to cold. The distinction between this normal physiology and Raynaud's phenomenon (RP) has yet to be well characterized. In anticipation of the 9th International Congress on Autoimmunity, a panel of 12 RP experts from 9 different institutes and four different countries were assembled for a Delphi exercise to establish new diagnostic criteria for RP. Relevant investigators with highly cited manuscripts in Raynaud's-related research were identified using the Web of Science and invited to participate. Surveys at each stage were administered to participants via the on-line SurveyMonkey software tool. The participants evaluated the level of appropriateness of statements using a scale of 1 (extremely inappropriate) through 9 (extremely appropriate). In the second stage, panel participants were asked to rank rewritten items from the first round that were scored as "uncertain" for the diagnosis of RP, items with significant disagreement (Disagreement Index > 1), and new items suggested by the panel. Results were analyzed using the Interpercentile Range Adjusted for Symmetry (IPRAS) method. A 3-Step Approach to diagnose RP was then developed using items the panelists "agreed" were "appropriate" diagnostic criteria. In the final stage, the panel was presented with the newly developed diagnostic criteria and asked to rate them against previous models. Following the first two iterations of the Delphi exercise, the panel of 12 experts agreed that 36 of the items were "appropriate", 12 items had "uncertain" appropriateness, and 13 items were "inappropriate" to use in the diagnostic criteria of RP. Using an expert committee, we developed a 3-Step Approach for the diagnosis of RP and 5 additional criteria for the diagnosis of primary RP. The committee came to an agreement that the proposed criteria were "appropriate and accurate" for use by physicians to diagnose patients with RP. (Less)
Please use this url to cite or link to this publication:
author
, et al. (More)
(Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Autoimmunity
volume
48-49
issue
Jan 31
pages
60 - 65
publisher
Elsevier
external identifiers
  • pmid:24491823
  • wos:000334009300013
  • scopus:84895882708
ISSN
0896-8411
DOI
10.1016/j.jaut.2014.01.020
language
English
LU publication?
yes
id
b64b869d-a152-447a-8276-5bf544501c94 (old id 4335739)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24491823?dopt=Abstract
date added to LUP
2014-03-06 22:46:02
date last changed
2017-11-05 03:10:49
@article{b64b869d-a152-447a-8276-5bf544501c94,
  abstract     = {Vasoconstriction accompanied by changes in skin color is a normal physiologic response to cold. The distinction between this normal physiology and Raynaud's phenomenon (RP) has yet to be well characterized. In anticipation of the 9th International Congress on Autoimmunity, a panel of 12 RP experts from 9 different institutes and four different countries were assembled for a Delphi exercise to establish new diagnostic criteria for RP. Relevant investigators with highly cited manuscripts in Raynaud's-related research were identified using the Web of Science and invited to participate. Surveys at each stage were administered to participants via the on-line SurveyMonkey software tool. The participants evaluated the level of appropriateness of statements using a scale of 1 (extremely inappropriate) through 9 (extremely appropriate). In the second stage, panel participants were asked to rank rewritten items from the first round that were scored as "uncertain" for the diagnosis of RP, items with significant disagreement (Disagreement Index > 1), and new items suggested by the panel. Results were analyzed using the Interpercentile Range Adjusted for Symmetry (IPRAS) method. A 3-Step Approach to diagnose RP was then developed using items the panelists "agreed" were "appropriate" diagnostic criteria. In the final stage, the panel was presented with the newly developed diagnostic criteria and asked to rate them against previous models. Following the first two iterations of the Delphi exercise, the panel of 12 experts agreed that 36 of the items were "appropriate", 12 items had "uncertain" appropriateness, and 13 items were "inappropriate" to use in the diagnostic criteria of RP. Using an expert committee, we developed a 3-Step Approach for the diagnosis of RP and 5 additional criteria for the diagnosis of primary RP. The committee came to an agreement that the proposed criteria were "appropriate and accurate" for use by physicians to diagnose patients with RP.},
  author       = {Maverakis, Emanual and Patel, Forum and Kronenberg, Daniel G and Chung, Lorinda and Fiorentino, David and Allanore, Yannick and Guiducci, Serena and Hesselstrand, Roger and Hummers, Laura K and Duong, Chris and Kahaleh, Bashar and Macgregor, Alexander and Matucci-Cerinic, Marco and Wollheim, Frank and Mayes, Maureen D and Gershwin, M Eric},
  issn         = {0896-8411},
  language     = {eng},
  number       = {Jan 31},
  pages        = {60--65},
  publisher    = {Elsevier},
  series       = {Journal of Autoimmunity},
  title        = {International consensus criteria for the diagnosis of Raynaud's phenomenon.},
  url          = {http://dx.doi.org/10.1016/j.jaut.2014.01.020},
  volume       = {48-49},
  year         = {2014},
}