Quality of Life and Economic Burden in Swedish Adults with Atopic Dermatitis : A Cross-sectional Survey of Patientreported Outcomes
(2026) In Acta Dermato-Venereologica 106.- Abstract
Atopic dermatitis (AD) is a chronic skin disease associated with impaired quality of life. Evidence from Sweden on out-of-pocket expenses and productivity losses remains limited. This study assessed the burden of AD among adults in relation to health-related quality of life (HRQoL), work productivity, activity impairment, willingness to pay for symptom relief, economic outcomes, considering comorbid asthma, allergies, depression and anxiety. A cross-sectional survey was conducted between 2024 and 2025 among 220 members of the Swedish Asthma and Allergy Patient Association. Validated instruments included the Dermatology Life Quality Index (DLQI), EuroQol five-dimensions, five-levels instrument (EQ-5D-5L), Patient Benefit Index, and Work... (More)
Atopic dermatitis (AD) is a chronic skin disease associated with impaired quality of life. Evidence from Sweden on out-of-pocket expenses and productivity losses remains limited. This study assessed the burden of AD among adults in relation to health-related quality of life (HRQoL), work productivity, activity impairment, willingness to pay for symptom relief, economic outcomes, considering comorbid asthma, allergies, depression and anxiety. A cross-sectional survey was conducted between 2024 and 2025 among 220 members of the Swedish Asthma and Allergy Patient Association. Validated instruments included the Dermatology Life Quality Index (DLQI), EuroQol five-dimensions, five-levels instrument (EQ-5D-5L), Patient Benefit Index, and Work Productivity and Activity Impairment questionnaire. Descriptive and regression analyses were performed. Respondents (89.8% female; mean age 43 years) reported moderate HRQoL impairment (mean DLQI 10.1). DLQI and EQ-5D-5L were worse among those with allergic or non-atopic comorbidities but did not differ by asthma status. Mean annual out-of-pocket costs and productivity losses were €900 (95% CI: 401.1–1,758.4) and €1,972 (95% CI: 1,198.7–2,828.0), respectively. Itch intensity and activity impairment were associated with lower HRQoL and higher costs. AD is related to worsened work and activity functioning and high economic burden, suggesting the need for improved support and management strategies for affected adults.
(Less)
- author
- Metsini, Alexandra ; Ryen, Linda ; Montgomery, Scott ; Molarius, Anu ; Svensson, Åke LU and von Kobyletzki, Laura LU
- organization
- publishing date
- 2026
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- atopic dermatitis, comorbidities, economic burden health-related quality of life, patient-reported outcomes, work productivity
- in
- Acta Dermato-Venereologica
- volume
- 106
- article number
- adv-2025-0184
- publisher
- Medical Journals Limited
- external identifiers
-
- pmid:41841275
- scopus:105033551629
- ISSN
- 0001-5555
- DOI
- 10.2340/actadv.v106.adv-2025-0184
- language
- English
- LU publication?
- yes
- id
- 43b1d8b2-4ac4-4440-abd7-c13dd5607032
- date added to LUP
- 2026-05-11 13:47:24
- date last changed
- 2026-05-25 14:43:25
@article{43b1d8b2-4ac4-4440-abd7-c13dd5607032,
abstract = {{<p>Atopic dermatitis (AD) is a chronic skin disease associated with impaired quality of life. Evidence from Sweden on out-of-pocket expenses and productivity losses remains limited. This study assessed the burden of AD among adults in relation to health-related quality of life (HRQoL), work productivity, activity impairment, willingness to pay for symptom relief, economic outcomes, considering comorbid asthma, allergies, depression and anxiety. A cross-sectional survey was conducted between 2024 and 2025 among 220 members of the Swedish Asthma and Allergy Patient Association. Validated instruments included the Dermatology Life Quality Index (DLQI), EuroQol five-dimensions, five-levels instrument (EQ-5D-5L), Patient Benefit Index, and Work Productivity and Activity Impairment questionnaire. Descriptive and regression analyses were performed. Respondents (89.8% female; mean age 43 years) reported moderate HRQoL impairment (mean DLQI 10.1). DLQI and EQ-5D-5L were worse among those with allergic or non-atopic comorbidities but did not differ by asthma status. Mean annual out-of-pocket costs and productivity losses were €900 (95% CI: 401.1–1,758.4) and €1,972 (95% CI: 1,198.7–2,828.0), respectively. Itch intensity and activity impairment were associated with lower HRQoL and higher costs. AD is related to worsened work and activity functioning and high economic burden, suggesting the need for improved support and management strategies for affected adults.</p>}},
author = {{Metsini, Alexandra and Ryen, Linda and Montgomery, Scott and Molarius, Anu and Svensson, Åke and von Kobyletzki, Laura}},
issn = {{0001-5555}},
keywords = {{atopic dermatitis; comorbidities; economic burden health-related quality of life; patient-reported outcomes; work productivity}},
language = {{eng}},
publisher = {{Medical Journals Limited}},
series = {{Acta Dermato-Venereologica}},
title = {{Quality of Life and Economic Burden in Swedish Adults with Atopic Dermatitis : A Cross-sectional Survey of Patientreported Outcomes}},
url = {{http://dx.doi.org/10.2340/actadv.v106.adv-2025-0184}},
doi = {{10.2340/actadv.v106.adv-2025-0184}},
volume = {{106}},
year = {{2026}},
}