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Assessment of projection interpolation to compensate for the increased radiation dose in DBTMI

Costa, Arthur C. LU ; Bjerkén, Anna LU orcid ; Dustler, Magnus LU ; Tingberg, Anders LU ; Bakic, Predrag LU and Vieira, Marcelo A.C. (2023) Medical Imaging 2023: Physics of Medical Imaging In Progress in Biomedical Optics and Imaging - Proceedings of SPIE 12463.
Abstract

The combination of digital breast tomosynthesis (DBT) with other imaging modalities has been investigated in order to improve the detection and diagnosis of breast cancer. Mechanical Imaging (MI) measures the stress over the surface of the compressed breast, using a pressure sensor, during radiographic examination and its response has shown a correlation with the presence of malignant lesions. Thus, the combination of DBT and MI (DBTMI) has shown potential to reduce false positive results in breast cancer screening. However, compared to the conventional DBT exam, the presence of the MI sensor during mammographic image acquisition may cause a slight increase in the radiation dose. This work presents a proposal to reduce the radiation... (More)

The combination of digital breast tomosynthesis (DBT) with other imaging modalities has been investigated in order to improve the detection and diagnosis of breast cancer. Mechanical Imaging (MI) measures the stress over the surface of the compressed breast, using a pressure sensor, during radiographic examination and its response has shown a correlation with the presence of malignant lesions. Thus, the combination of DBT and MI (DBTMI) has shown potential to reduce false positive results in breast cancer screening. However, compared to the conventional DBT exam, the presence of the MI sensor during mammographic image acquisition may cause a slight increase in the radiation dose. This work presents a proposal to reduce the radiation dose in DBTMI exams by removing some projections from the original set and replacing them with synthetic projections generated by a video frame interpolation (VFI) neural network. We compared several DBTMI acquisition arrangements, considering the removal of 16% of the original projections, using a deformable physical breast phantom, and evaluated the quality of the reconstructed images based on the Normalized Root Mean Squared Error (NRMSE). The results showed that, for some arrangements, the slices reconstructed with the addition of synthetic DBTMI projections presented better quality than when they were reconstructed with the reduced set of projections. Further studies must be carried out to optimize the interpolation approach.

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author
; ; ; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
deep learning, digital breast tomosynthesis, mechanical imaging, neural network, radiation dose, video frame interpolation
host publication
Medical Imaging 2023 : Physics of Medical Imaging - Physics of Medical Imaging
series title
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
editor
Yu, Lifeng ; Fahrig, Rebecca and Sabol, John M.
volume
12463
article number
1246344
publisher
SPIE
conference name
Medical Imaging 2023: Physics of Medical Imaging
conference location
San Diego, United States
conference dates
2023-02-19 - 2023-02-23
external identifiers
  • scopus:85160721783
ISSN
1605-7422
ISBN
9781510660311
DOI
10.1117/12.2655006
language
English
LU publication?
yes
id
43b6d48e-396b-4b6b-8c0c-36c0b60854ee
date added to LUP
2023-08-30 13:56:31
date last changed
2023-08-31 09:09:00
@inproceedings{43b6d48e-396b-4b6b-8c0c-36c0b60854ee,
  abstract     = {{<p>The combination of digital breast tomosynthesis (DBT) with other imaging modalities has been investigated in order to improve the detection and diagnosis of breast cancer. Mechanical Imaging (MI) measures the stress over the surface of the compressed breast, using a pressure sensor, during radiographic examination and its response has shown a correlation with the presence of malignant lesions. Thus, the combination of DBT and MI (DBTMI) has shown potential to reduce false positive results in breast cancer screening. However, compared to the conventional DBT exam, the presence of the MI sensor during mammographic image acquisition may cause a slight increase in the radiation dose. This work presents a proposal to reduce the radiation dose in DBTMI exams by removing some projections from the original set and replacing them with synthetic projections generated by a video frame interpolation (VFI) neural network. We compared several DBTMI acquisition arrangements, considering the removal of 16% of the original projections, using a deformable physical breast phantom, and evaluated the quality of the reconstructed images based on the Normalized Root Mean Squared Error (NRMSE). The results showed that, for some arrangements, the slices reconstructed with the addition of synthetic DBTMI projections presented better quality than when they were reconstructed with the reduced set of projections. Further studies must be carried out to optimize the interpolation approach.</p>}},
  author       = {{Costa, Arthur C. and Bjerkén, Anna and Dustler, Magnus and Tingberg, Anders and Bakic, Predrag and Vieira, Marcelo A.C.}},
  booktitle    = {{Medical Imaging 2023 : Physics of Medical Imaging}},
  editor       = {{Yu, Lifeng and Fahrig, Rebecca and Sabol, John M.}},
  isbn         = {{9781510660311}},
  issn         = {{1605-7422}},
  keywords     = {{deep learning; digital breast tomosynthesis; mechanical imaging; neural network; radiation dose; video frame interpolation}},
  language     = {{eng}},
  publisher    = {{SPIE}},
  series       = {{Progress in Biomedical Optics and Imaging - Proceedings of SPIE}},
  title        = {{Assessment of projection interpolation to compensate for the increased radiation dose in DBTMI}},
  url          = {{http://dx.doi.org/10.1117/12.2655006}},
  doi          = {{10.1117/12.2655006}},
  volume       = {{12463}},
  year         = {{2023}},
}