An integrated thermal biosensor array for multianalyte determination demonstrated with glucose, urea and penicillin
(1996) In Analytical Letters 29(11). p.1921-1932- Abstract
An integrated thermal biosensor array was designed and fabricated for
the simultaneous determination of glucose, urea and penicillin. The
sensor contains six thin-film thermistors which were fabricated on
quartz chip by micromachining and semiconductor technology. This sensor
allows the determination of three different analytes nearly
simultaneously by serially partitioning a single microchannel into three
distinct detection regions. Each of the regions contained one
immobilized enzyme matrix and a pair of thermistors for differential
measurement of temperature changes in association with the enzyme
reactions. Using this device, glucose, urea and penicillin-G at
different concentrations... (More)An integrated thermal biosensor array was designed and fabricated for
(Less)
the simultaneous determination of glucose, urea and penicillin. The
sensor contains six thin-film thermistors which were fabricated on
quartz chip by micromachining and semiconductor technology. This sensor
allows the determination of three different analytes nearly
simultaneously by serially partitioning a single microchannel into three
distinct detection regions. Each of the regions contained one
immobilized enzyme matrix and a pair of thermistors for differential
measurement of temperature changes in association with the enzyme
reactions. Using this device, glucose, urea and penicillin-G at
different concentrations were determined in the mixed samples. Linear
ranges of 1 to at least 25 mM urea and penicillin, and up to 20 mM
glucose were obtained using a sample volume of 20 μL.
- author
- Xie, Bin LU and Danielsson, Bengt LU
- organization
- publishing date
- 1996
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Glucose, Multianalyte determination, Penicillin, Sensor array, Thermal biosensor, Urea
- in
- Analytical Letters
- volume
- 29
- issue
- 11
- pages
- 12 pages
- publisher
- Taylor & Francis
- external identifiers
-
- scopus:0001757291
- ISSN
- 0003-2719
- DOI
- 10.1080/00032719608000798
- language
- English
- LU publication?
- yes
- id
- 44023d1e-ae87-4911-8f8b-3b70f95c8d17
- date added to LUP
- 2021-10-27 15:46:17
- date last changed
- 2022-03-11 21:00:18
@article{44023d1e-ae87-4911-8f8b-3b70f95c8d17,
abstract = {{<p>An integrated thermal biosensor array was designed and fabricated for <br>
the simultaneous determination of glucose, urea and penicillin. The <br>
sensor contains six thin-film thermistors which were fabricated on <br>
quartz chip by micromachining and semiconductor technology. This sensor <br>
allows the determination of three different analytes nearly <br>
simultaneously by serially partitioning a single microchannel into three<br>
distinct detection regions. Each of the regions contained one <br>
immobilized enzyme matrix and a pair of thermistors for differential <br>
measurement of temperature changes in association with the enzyme <br>
reactions. Using this device, glucose, urea and penicillin-G at <br>
different concentrations were determined in the mixed samples. Linear <br>
ranges of 1 to at least 25 mM urea and penicillin, and up to 20 mM <br>
glucose were obtained using a sample volume of 20 μL.</p>}},
author = {{Xie, Bin and Danielsson, Bengt}},
issn = {{0003-2719}},
keywords = {{Glucose; Multianalyte determination; Penicillin; Sensor array; Thermal biosensor; Urea}},
language = {{eng}},
number = {{11}},
pages = {{1921--1932}},
publisher = {{Taylor & Francis}},
series = {{Analytical Letters}},
title = {{An integrated thermal biosensor array for multianalyte determination demonstrated with glucose, urea and penicillin}},
url = {{http://dx.doi.org/10.1080/00032719608000798}},
doi = {{10.1080/00032719608000798}},
volume = {{29}},
year = {{1996}},
}