Use of a standardized diagnostic approach improves the prognostic information of histopathologic factors in pancreatic and periampullary adenocarcinoma.
Elebro, Jacob LU and Jirström, Karin LU
(2014)
In Diagnostic Pathology
9(1).
- Abstract
- Variability in reported histopathology parameters in operated periampullary adenocarcinomas may affect the prognostic weight of the parameters. Standardized axial sectioning produces a higher incidence of involved margins and also seems to produce a lower relative incidence of pancreatic compared with distal bile duct origin and a higher incidence of involved lymph nodes, compared with non-standardized procedure. The aims of this study were to 1) assess how a previously not described standardized pathology procedure, with longitudinal sectioning along the distal bile duct, affects reported tumour origin, margin status and involved lymph nodes, compared with non-standardized procedure, 2) assess if re-evaluation of microscopic slides... (More)
- Variability in reported histopathology parameters in operated periampullary adenocarcinomas may affect the prognostic weight of the parameters. Standardized axial sectioning produces a higher incidence of involved margins and also seems to produce a lower relative incidence of pancreatic compared with distal bile duct origin and a higher incidence of involved lymph nodes, compared with non-standardized procedure. The aims of this study were to 1) assess how a previously not described standardized pathology procedure, with longitudinal sectioning along the distal bile duct, affects reported tumour origin, margin status and involved lymph nodes, compared with non-standardized procedure, 2) assess if re-evaluation of microscopic slides affects the prognostic value of margin status and 3) compare the results of this standardized procedure with reported results of other standardized and non-standardized procedures. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4430076
- author
- Elebro, Jacob
LU
and Jirström, Karin
LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Diagnostic Pathology
- volume
- 9
- issue
- 1
- article number
- 80
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:24731283
- wos:000335186900001
- scopus:84899656267
- pmid:24731283
- ISSN
- 1746-1596
- DOI
- 10.1186/1746-1596-9-80
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pathology, (Lund) (013030000)
- id
- 43d76bf4-6a45-474c-ac3c-ce595e6d07e5 (old id 4430076)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24731283?dopt=Abstract
- date added to LUP
- 2016-04-01 14:34:43
- date last changed
- 2024-01-29 02:56:16
@article{43d76bf4-6a45-474c-ac3c-ce595e6d07e5,
abstract = {{Variability in reported histopathology parameters in operated periampullary adenocarcinomas may affect the prognostic weight of the parameters. Standardized axial sectioning produces a higher incidence of involved margins and also seems to produce a lower relative incidence of pancreatic compared with distal bile duct origin and a higher incidence of involved lymph nodes, compared with non-standardized procedure. The aims of this study were to 1) assess how a previously not described standardized pathology procedure, with longitudinal sectioning along the distal bile duct, affects reported tumour origin, margin status and involved lymph nodes, compared with non-standardized procedure, 2) assess if re-evaluation of microscopic slides affects the prognostic value of margin status and 3) compare the results of this standardized procedure with reported results of other standardized and non-standardized procedures.}},
author = {{Elebro, Jacob and Jirström, Karin}},
issn = {{1746-1596}},
language = {{eng}},
number = {{1}},
publisher = {{BioMed Central (BMC)}},
series = {{Diagnostic Pathology}},
title = {{Use of a standardized diagnostic approach improves the prognostic information of histopathologic factors in pancreatic and periampullary adenocarcinoma.}},
url = {{https://lup.lub.lu.se/search/files/4046354/4882743}},
doi = {{10.1186/1746-1596-9-80}},
volume = {{9}},
year = {{2014}},
}