Small Distal Muscles and Balance Predict Survival in End-Stage Renal Disease.
Hellberg, Matthias LU ; Wiberg, Eva Maria ; Simonsen, Ole LU ; Höglund, Peter LU and Clyne, Naomi LU
(2014)
In Nephron Clinical Practice
126(3).
p.116-123
- Abstract
- Background/Aims: Survival for patients on renal replacement therapy (RRT) has been shown to correlate to the level of physical activity and exercise capacity. We examined whether composite measures of functional status at the start of RRT predict survival. Methods: In this retrospective study, the same physiotherapist, using a standardized battery of tests for functional status, tested 134 patients at the start of RRT. Results: At the end of the observation period, 112 patients (84%) were still alive. Age (p < 0.0001), co-morbidity (p = 0.028), hand grip strength (right: p = 0.0065; left: p = 0.0039), standing heel rise (right: p = 0.011; left: p = 0.004) and functional reach (p = 0.015) were significant predictors of survival. After... (More)
- Background/Aims: Survival for patients on renal replacement therapy (RRT) has been shown to correlate to the level of physical activity and exercise capacity. We examined whether composite measures of functional status at the start of RRT predict survival. Methods: In this retrospective study, the same physiotherapist, using a standardized battery of tests for functional status, tested 134 patients at the start of RRT. Results: At the end of the observation period, 112 patients (84%) were still alive. Age (p < 0.0001), co-morbidity (p = 0.028), hand grip strength (right: p = 0.0065; left: p = 0.0039), standing heel rise (right: p = 0.011; left: p = 0.004) and functional reach (p = 0.015) were significant predictors of survival. After adjustment for sex, age and co-morbidity, hand grip strength left (p = 0.023) was a significant predictor of survival. Conclusion: Hand grip strength, standing heel rise and functional reach at the start of RRT seem to affect survival. A 50% reduction in hand grip strength left was associated with an almost 3-fold increase in mortality. Deterioration of function in small distal muscles and balance may be early signs of uraemic myopathy. A relatively simple and clinically feasible battery of tests can help detect patients at risk. © 2014 S. Karger AG, Basel. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4430601
- author
- Hellberg, Matthias
LU
; Wiberg, Eva Maria
; Simonsen, Ole
LU
; Höglund, Peter
LU
and Clyne, Naomi
LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Nephron Clinical Practice
- volume
- 126
- issue
- 3
- pages
- 116 - 123
- publisher
- Karger
- external identifiers
-
- pmid:24713811
- wos:000338363900003
- scopus:84897358028
- ISSN
- 1660-2110
- DOI
- 10.1159/000358431
- language
- English
- LU publication?
- yes
- id
- 975257cb-3196-468c-9b10-a458e90408c8 (old id 4430601)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24713811?dopt=Abstract
- date added to LUP
- 2016-04-01 10:28:55
- date last changed
- 2022-03-12 06:19:08
@article{975257cb-3196-468c-9b10-a458e90408c8,
abstract = {{Background/Aims: Survival for patients on renal replacement therapy (RRT) has been shown to correlate to the level of physical activity and exercise capacity. We examined whether composite measures of functional status at the start of RRT predict survival. Methods: In this retrospective study, the same physiotherapist, using a standardized battery of tests for functional status, tested 134 patients at the start of RRT. Results: At the end of the observation period, 112 patients (84%) were still alive. Age (p < 0.0001), co-morbidity (p = 0.028), hand grip strength (right: p = 0.0065; left: p = 0.0039), standing heel rise (right: p = 0.011; left: p = 0.004) and functional reach (p = 0.015) were significant predictors of survival. After adjustment for sex, age and co-morbidity, hand grip strength left (p = 0.023) was a significant predictor of survival. Conclusion: Hand grip strength, standing heel rise and functional reach at the start of RRT seem to affect survival. A 50% reduction in hand grip strength left was associated with an almost 3-fold increase in mortality. Deterioration of function in small distal muscles and balance may be early signs of uraemic myopathy. A relatively simple and clinically feasible battery of tests can help detect patients at risk. © 2014 S. Karger AG, Basel.}},
author = {{Hellberg, Matthias and Wiberg, Eva Maria and Simonsen, Ole and Höglund, Peter and Clyne, Naomi}},
issn = {{1660-2110}},
language = {{eng}},
number = {{3}},
pages = {{116--123}},
publisher = {{Karger}},
series = {{Nephron Clinical Practice}},
title = {{Small Distal Muscles and Balance Predict Survival in End-Stage Renal Disease.}},
url = {{http://dx.doi.org/10.1159/000358431}},
doi = {{10.1159/000358431}},
volume = {{126}},
year = {{2014}},
}