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Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.

Bruze, Magnus LU ; Isaksson, Marléne LU ; Gruvberger, Birgitta LU ; Andersen, Klaus E; Gonçalo, Margarida; Goossens, An; Johansen, Jeanne D; Maibach, Howard I; Rustemeyer, Thomas and Le Coz, Christophe-J, et al. (2014) In Contact Dermatitis 71(1). p.31-34
Abstract
Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are the active ingredients in commonly used preservative systems (e.g. Kathon CG(®) ). MCI/MI is present in the European baseline patch test series at 100 ppm aq. Since 1986, 200 ppm (dose 0.006 mg/cm(2) ) has been used in Sweden without causing skin irritation. Centres in Spain, the United Kingdom and Ireland have also used 200 ppm in their baseline series.
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type
Contribution to journal
publication status
published
subject
in
Contact Dermatitis
volume
71
issue
1
pages
31 - 34
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • pmid:24712418
  • wos:000339724800004
  • scopus:84902535679
ISSN
0105-1873
DOI
10.1111/cod.12241
language
English
LU publication?
yes
id
9dd4771f-0b22-4f5b-9a97-c869d629ffb7 (old id 4430657)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24712418?dopt=Abstract
date added to LUP
2014-05-06 19:23:43
date last changed
2017-10-01 03:32:42
@article{9dd4771f-0b22-4f5b-9a97-c869d629ffb7,
  abstract     = {Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are the active ingredients in commonly used preservative systems (e.g. Kathon CG(®) ). MCI/MI is present in the European baseline patch test series at 100 ppm aq. Since 1986, 200 ppm (dose 0.006 mg/cm(2) ) has been used in Sweden without causing skin irritation. Centres in Spain, the United Kingdom and Ireland have also used 200 ppm in their baseline series.},
  author       = {Bruze, Magnus and Isaksson, Marléne and Gruvberger, Birgitta and Andersen, Klaus E and Gonçalo, Margarida and Goossens, An and Johansen, Jeanne D and Maibach, Howard I and Rustemeyer, Thomas and Le Coz, Christophe-J and White, Ian R},
  issn         = {0105-1873},
  language     = {eng},
  number       = {1},
  pages        = {31--34},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {Contact Dermatitis},
  title        = {Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.},
  url          = {http://dx.doi.org/10.1111/cod.12241},
  volume       = {71},
  year         = {2014},
}