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Induction of T helper 2 responses against human Apolipoprotein B100 does not affect atherosclerosis in ApoE-/- mice.

Engelbertsen, Daniel LU ; Rattik, Sara LU ; Knutsson, Anki LU ; Björkbacka, Harry LU ; Bengtsson, Eva LU and Nilsson, Jan LU (2014) In Cardiovascular Research
Abstract
Immune responses against LDL antigens have been found to play an important modulatory role in atherosclerosis. Immunization with homologous oxidized LDL, as well as human apolipoprotein B100 (ApoB)-derived peptides, inhibit atherosclerosis in hypercholesterolemic animal models of atherosclerosis. However, the role of antigen-specific Th2 responses in atherosclerosis remains to be fully clarified.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Cardiovascular Research
publisher
Elsevier
external identifiers
  • pmid:24866382
  • scopus:84904319344
ISSN
1755-3245
DOI
10.1093/cvr/cvu131
language
English
LU publication?
yes
id
7cfb0949-6a75-4f6d-a20e-2d6e17c05892 (old id 4452469)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24866382?dopt=Abstract
date added to LUP
2014-06-06 21:09:11
date last changed
2017-11-12 04:05:44
@article{7cfb0949-6a75-4f6d-a20e-2d6e17c05892,
  abstract     = {Immune responses against LDL antigens have been found to play an important modulatory role in atherosclerosis. Immunization with homologous oxidized LDL, as well as human apolipoprotein B100 (ApoB)-derived peptides, inhibit atherosclerosis in hypercholesterolemic animal models of atherosclerosis. However, the role of antigen-specific Th2 responses in atherosclerosis remains to be fully clarified.},
  author       = {Engelbertsen, Daniel and Rattik, Sara and Knutsson, Anki and Björkbacka, Harry and Bengtsson, Eva and Nilsson, Jan},
  issn         = {1755-3245},
  language     = {eng},
  month        = {05},
  publisher    = {Elsevier},
  series       = {Cardiovascular Research},
  title        = {Induction of T helper 2 responses against human Apolipoprotein B100 does not affect atherosclerosis in ApoE-/- mice.},
  url          = {http://dx.doi.org/10.1093/cvr/cvu131},
  year         = {2014},
}