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Nitrosative modifications of the Ca2+ release complex and actin underlie arthritis-induced muscle weakness.

Yamada, Takashi ; Fedotovskaya, Olga ; Cheng, Arthur J ; Cornachione, Anabelle S ; Minozzo, Fabio C ; Aulin, Cecilia ; Fridén, Cecilia ; Turesson, Carl LU ; Andersson, Daniel C and Glenmark, Birgitta , et al. (2015) In Annals of the Rheumatic Diseases 74(10). p.1907-1914
Abstract
Skeletal muscle weakness is a prominent clinical feature in patients with rheumatoid arthritis (RA), but the underlying mechanism(s) is unknown. Here we investigate the mechanisms behind arthritis-induced skeletal muscle weakness with special focus on the role of nitrosative stress on intracellular Ca(2+) handling and specific force production.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Annals of the Rheumatic Diseases
volume
74
issue
10
pages
1907 - 1914
publisher
BMJ Publishing Group
external identifiers
  • pmid:24854355
  • wos:000361043200022
  • scopus:84942849874
  • pmid:24854355
ISSN
1468-2060
DOI
10.1136/annrheumdis-2013-205007
language
English
LU publication?
yes
id
d106d588-33a7-4f78-ae16-5b9078833b90 (old id 4452661)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24854355?dopt=Abstract
date added to LUP
2016-04-01 10:43:13
date last changed
2022-04-28 00:44:24
@article{d106d588-33a7-4f78-ae16-5b9078833b90,
  abstract     = {{Skeletal muscle weakness is a prominent clinical feature in patients with rheumatoid arthritis (RA), but the underlying mechanism(s) is unknown. Here we investigate the mechanisms behind arthritis-induced skeletal muscle weakness with special focus on the role of nitrosative stress on intracellular Ca(2+) handling and specific force production.}},
  author       = {{Yamada, Takashi and Fedotovskaya, Olga and Cheng, Arthur J and Cornachione, Anabelle S and Minozzo, Fabio C and Aulin, Cecilia and Fridén, Cecilia and Turesson, Carl and Andersson, Daniel C and Glenmark, Birgitta and Lundberg, Ingrid E and Rassier, Dilson E and Westerblad, Håkan and Lanner, Johanna T}},
  issn         = {{1468-2060}},
  language     = {{eng}},
  number       = {{10}},
  pages        = {{1907--1914}},
  publisher    = {{BMJ Publishing Group}},
  series       = {{Annals of the Rheumatic Diseases}},
  title        = {{Nitrosative modifications of the Ca2+ release complex and actin underlie arthritis-induced muscle weakness.}},
  url          = {{http://dx.doi.org/10.1136/annrheumdis-2013-205007}},
  doi          = {{10.1136/annrheumdis-2013-205007}},
  volume       = {{74}},
  year         = {{2015}},
}