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Nitrosative modifications of the Ca2+ release complex and actin underlie arthritis-induced muscle weakness.

Yamada, Takashi; Fedotovskaya, Olga; Cheng, Arthur J; Cornachione, Anabelle S; Minozzo, Fabio C; Aulin, Cecilia; Fridén, Cecilia; Turesson, Carl LU ; Andersson, Daniel C and Glenmark, Birgitta, et al. (2015) In Annals of the Rheumatic Diseases 74(10). p.1907-1914
Abstract
Skeletal muscle weakness is a prominent clinical feature in patients with rheumatoid arthritis (RA), but the underlying mechanism(s) is unknown. Here we investigate the mechanisms behind arthritis-induced skeletal muscle weakness with special focus on the role of nitrosative stress on intracellular Ca(2+) handling and specific force production.
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Contribution to journal
publication status
published
subject
in
Annals of the Rheumatic Diseases
volume
74
issue
10
pages
1907 - 1914
publisher
British Medical Association
external identifiers
  • pmid:24854355
  • wos:000361043200022
  • scopus:84942849874
ISSN
1468-2060
DOI
10.1136/annrheumdis-2013-205007
language
English
LU publication?
yes
id
d106d588-33a7-4f78-ae16-5b9078833b90 (old id 4452661)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24854355?dopt=Abstract
date added to LUP
2014-06-06 20:08:38
date last changed
2017-11-12 03:11:31
@article{d106d588-33a7-4f78-ae16-5b9078833b90,
  abstract     = {Skeletal muscle weakness is a prominent clinical feature in patients with rheumatoid arthritis (RA), but the underlying mechanism(s) is unknown. Here we investigate the mechanisms behind arthritis-induced skeletal muscle weakness with special focus on the role of nitrosative stress on intracellular Ca(2+) handling and specific force production.},
  author       = {Yamada, Takashi and Fedotovskaya, Olga and Cheng, Arthur J and Cornachione, Anabelle S and Minozzo, Fabio C and Aulin, Cecilia and Fridén, Cecilia and Turesson, Carl and Andersson, Daniel C and Glenmark, Birgitta and Lundberg, Ingrid E and Rassier, Dilson E and Westerblad, Håkan and Lanner, Johanna T},
  issn         = {1468-2060},
  language     = {eng},
  number       = {10},
  pages        = {1907--1914},
  publisher    = {British Medical Association},
  series       = {Annals of the Rheumatic Diseases},
  title        = {Nitrosative modifications of the Ca2+ release complex and actin underlie arthritis-induced muscle weakness.},
  url          = {http://dx.doi.org/10.1136/annrheumdis-2013-205007},
  volume       = {74},
  year         = {2015},
}