Advanced

Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study.

Langenberg, Claudia; Sharp, Stephen J; Franks, Paul LU ; Scott, Robert A; Deloukas, Panos; Forouhi, Nita G; Froguel, Philippe; Groop, Leif LU ; Hansen, Torben and Palla, Luigi, et al. (2014) In PLoS Medicine 11(5).
Abstract
Understanding of the genetic basis of type 2 diabetes (T2D) has progressed rapidly, but the interactions between common genetic variants and lifestyle risk factors have not been systematically investigated in studies with adequate statistical power. Therefore, we aimed to quantify the combined effects of genetic and lifestyle factors on risk of T2D in order to inform strategies for prevention.
Please use this url to cite or link to this publication:
author
, et al. (More)
(Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS Medicine
volume
11
issue
5
publisher
Public Library of Science
external identifiers
  • pmid:24845081
  • wos:000337349300009
  • scopus:84901387060
ISSN
1549-1676
DOI
10.1371/journal.pmed.1001647
language
English
LU publication?
yes
id
c2c34b2e-6d9f-4622-8b97-aff385f651f7 (old id 4454047)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24845081?dopt=Abstract
date added to LUP
2014-06-04 22:15:04
date last changed
2017-10-01 03:17:42
@article{c2c34b2e-6d9f-4622-8b97-aff385f651f7,
  abstract     = {Understanding of the genetic basis of type 2 diabetes (T2D) has progressed rapidly, but the interactions between common genetic variants and lifestyle risk factors have not been systematically investigated in studies with adequate statistical power. Therefore, we aimed to quantify the combined effects of genetic and lifestyle factors on risk of T2D in order to inform strategies for prevention.},
  articleno    = {e1001647},
  author       = {Langenberg, Claudia and Sharp, Stephen J and Franks, Paul and Scott, Robert A and Deloukas, Panos and Forouhi, Nita G and Froguel, Philippe and Groop, Leif and Hansen, Torben and Palla, Luigi and Pedersen, Oluf and Schulze, Matthias B and Tormo, Maria-Jose and Wheeler, Eleanor and Agnoli, Claudia and Arriola, Larraitz and Barricarte, Aurelio and Boeing, Heiner and Clarke, Geraldine M and Clavel-Chapelon, Françoise and Duell, Eric J and Fagherazzi, Guy and Kaaks, Rudolf and Kerrison, Nicola D and Key, Timothy J and Khaw, Kay Tee and Kröger, Janine and Lajous, Martin and Morris, Andrew P and Navarro, Carmen and Nilsson, Peter and Overvad, Kim and Palli, Domenico and Panico, Salvatore and Quirós, J Ramón and Rolandsson, Olov and Sacerdote, Carlotta and Sánchez, María-José and Slimani, Nadia and Spijkerman, Annemieke M W and Tumino, Rosario and van der A, Daphne L and van der Schouw, Yvonne T and Barroso, Inês and McCarthy, Mark I and Riboli, Elio and Wareham, Nicholas J},
  issn         = {1549-1676},
  language     = {eng},
  number       = {5},
  publisher    = {Public Library of Science},
  series       = {PLoS Medicine},
  title        = {Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study.},
  url          = {http://dx.doi.org/10.1371/journal.pmed.1001647},
  volume       = {11},
  year         = {2014},
}