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Contribution of pseudogenes to sequence diversity.

Vihinen, Mauno LU (2014) In Pseudogenes. Functions and Protocols. p.15-24
Abstract
Pseudogenes are very common in the genomes of a wide range of organisms and, although they were originally considered as genetic junk, now several functions have been attributed to them. One important function of pseudogenes, as discussed in this chapter, is to provide material for genetic diversity. This is most prominent in the case of immunological recognition molecules such as immunoglobulins and B- and T-cell receptors, as well as in the case of antigenic variation in intracellular pathogens. Other examples discussed are olfactory receptors, ribosomal proteins, cytochrome P450s, and pseudokinases.
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author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
in
Pseudogenes. Functions and Protocols.
editor
Poliseno, Laura and
pages
15 - 24
publisher
Springer
external identifiers
  • pmid:24823768
  • scopus:84922280585
ISBN
978-1-4939-0835-6
DOI
10.1007/978-1-4939-0835-6_2
language
English
LU publication?
yes
id
7cdc7d39-50c3-4244-a8e9-56f68a4c0837 (old id 4455311)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24823768?dopt=Abstract
date added to LUP
2014-06-03 23:43:27
date last changed
2017-01-01 08:06:34
@inbook{7cdc7d39-50c3-4244-a8e9-56f68a4c0837,
  abstract     = {Pseudogenes are very common in the genomes of a wide range of organisms and, although they were originally considered as genetic junk, now several functions have been attributed to them. One important function of pseudogenes, as discussed in this chapter, is to provide material for genetic diversity. This is most prominent in the case of immunological recognition molecules such as immunoglobulins and B- and T-cell receptors, as well as in the case of antigenic variation in intracellular pathogens. Other examples discussed are olfactory receptors, ribosomal proteins, cytochrome P450s, and pseudokinases.},
  author       = {Vihinen, Mauno},
  editor       = {Poliseno, Laura},
  isbn         = {978-1-4939-0835-6},
  language     = {eng},
  pages        = {15--24},
  publisher    = {Springer},
  series       = {Pseudogenes. Functions and Protocols.},
  title        = {Contribution of pseudogenes to sequence diversity.},
  url          = {http://dx.doi.org/10.1007/978-1-4939-0835-6_2},
  year         = {2014},
}