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ABO blood group does not impact incidence or outcomes of surgery for acute type A aortic dissection

Nozohoor, Shahab LU ; Ahmad, Khalil ; Bjurbom, Markus ; Hansson, Emma C. ; Heimisdottir, Alexandra ; Jeppsson, Anders ; Mennander, Ari ; Olsson, Christian LU ; Pan, Emily and Ragnarsson, Sigurdur LU , et al. (2020) In Scandinavian Cardiovascular Journal 54(2). p.124-129
Abstract

Objectives. To evaluate the distribution and impact of ABO blood groups on postoperative outcomes in patients undergoing surgery for acute type A aortic dissection (ATAAD). Design. A total of 1144 surgical ATAAD patients from eight Nordic centres constituting the Nordic consortium for acute type A aortic dissection (NORCAAD) were analysed. Blood group O patients were compared to non-O subjects. The relative frequency of blood groups was assessed with t-distribution, modified for weighted proportions. Multivariable logistic regression was performed to identify independent predictors of 30-day mortality. Cox regression analyses were performed for assessing independent predictors of late mortality. Results. There was no significant... (More)

Objectives. To evaluate the distribution and impact of ABO blood groups on postoperative outcomes in patients undergoing surgery for acute type A aortic dissection (ATAAD). Design. A total of 1144 surgical ATAAD patients from eight Nordic centres constituting the Nordic consortium for acute type A aortic dissection (NORCAAD) were analysed. Blood group O patients were compared to non-O subjects. The relative frequency of blood groups was assessed with t-distribution, modified for weighted proportions. Multivariable logistic regression was performed to identify independent predictors of 30-day mortality. Cox regression analyses were performed for assessing independent predictors of late mortality. Results. There was no significant difference in the proportions of blood group O between the study populations in the NORCAAD registry and the background population (40.6 (95% CI 37.7–43.4)% vs 39.0 (95% CI 39.0–39.0)%). ABO blood group was not associated with any significant change in risk of 30-day or late mortality, with the exception of blood group A being an independent predictor of late mortality. Prevalence of postoperative complications was similar between the ABO blood groups. Conclusions. In this large cohort of Nordic ATAAD patients, there were no associations between ABO blood group and surgical incidence or outcomes, including postoperative complications and survival.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
aneurysm, Aorta, blood group, dissection, NORCAAD
in
Scandinavian Cardiovascular Journal
volume
54
issue
2
pages
6 pages
publisher
Taylor & Francis
external identifiers
  • pmid:31642332
  • scopus:85074484296
ISSN
1401-7431
DOI
10.1080/14017431.2019.1679387
language
English
LU publication?
yes
id
44653888-4a90-45d6-95ae-1200e044e103
date added to LUP
2019-11-25 14:19:04
date last changed
2021-02-23 04:32:38
@article{44653888-4a90-45d6-95ae-1200e044e103,
  abstract     = {<p>Objectives. To evaluate the distribution and impact of ABO blood groups on postoperative outcomes in patients undergoing surgery for acute type A aortic dissection (ATAAD). Design. A total of 1144 surgical ATAAD patients from eight Nordic centres constituting the Nordic consortium for acute type A aortic dissection (NORCAAD) were analysed. Blood group O patients were compared to non-O subjects. The relative frequency of blood groups was assessed with t-distribution, modified for weighted proportions. Multivariable logistic regression was performed to identify independent predictors of 30-day mortality. Cox regression analyses were performed for assessing independent predictors of late mortality. Results. There was no significant difference in the proportions of blood group O between the study populations in the NORCAAD registry and the background population (40.6 (95% CI 37.7–43.4)% vs 39.0 (95% CI 39.0–39.0)%). ABO blood group was not associated with any significant change in risk of 30-day or late mortality, with the exception of blood group A being an independent predictor of late mortality. Prevalence of postoperative complications was similar between the ABO blood groups. Conclusions. In this large cohort of Nordic ATAAD patients, there were no associations between ABO blood group and surgical incidence or outcomes, including postoperative complications and survival.</p>},
  author       = {Nozohoor, Shahab and Ahmad, Khalil and Bjurbom, Markus and Hansson, Emma C. and Heimisdottir, Alexandra and Jeppsson, Anders and Mennander, Ari and Olsson, Christian and Pan, Emily and Ragnarsson, Sigurdur and Sjögren, Johan and Tellides, George and Wickbom, Anders and Geirsson, Arnar and Gudbjartsson, Tomas and Zindovic, Igor},
  issn         = {1401-7431},
  language     = {eng},
  number       = {2},
  pages        = {124--129},
  publisher    = {Taylor & Francis},
  series       = {Scandinavian Cardiovascular Journal},
  title        = {ABO blood group does not impact incidence or outcomes of surgery for acute type A aortic dissection},
  url          = {http://dx.doi.org/10.1080/14017431.2019.1679387},
  doi          = {10.1080/14017431.2019.1679387},
  volume       = {54},
  year         = {2020},
}