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Simultaneous digital breast tomosynthesis and mechanical imaging in women recalled from screening - A preliminary analysis

Axelsson, Rebecca LU ; Dahlblom, Victor LU orcid ; Tingberg, Anders LU orcid ; Zackrisson, Sophia LU ; Dustler, Magnus LU and Bakic, Predrag LU (2022) 16th International Workshop on Breast Imaging, IWBI 2022 In Proceedings of SPIE - The International Society for Optical Engineering 12286.
Abstract

We have developed a method for simultaneous tomosynthesis and mechanical imaging, called DBTMI. Mechanical imaging measures the stress distribution over the compressed breast surface. Malignant tissue is usually stiffer than benign, which results in higher stress on the compressed breast and enables to distinguish malignant from benign findings. By combining tomosynthesis and mechanical imaging, we could improve cancer detection accuracy by reducing the number of false positive findings. In this study we have analysed clinical DBTMI data, collected from 52 women from an ongoing pilot study at the Skåne University Hospital, Malmö, Sweden. We measured the range of the average stress over the breast surface, the range of average stress... (More)

We have developed a method for simultaneous tomosynthesis and mechanical imaging, called DBTMI. Mechanical imaging measures the stress distribution over the compressed breast surface. Malignant tissue is usually stiffer than benign, which results in higher stress on the compressed breast and enables to distinguish malignant from benign findings. By combining tomosynthesis and mechanical imaging, we could improve cancer detection accuracy by reducing the number of false positive findings. In this study we have analysed clinical DBTMI data, collected from 52 women from an ongoing pilot study at the Skåne University Hospital, Malmö, Sweden. We measured the range of the average stress over the breast surface, the range of average stress over the location of suspected lesions, and the normalized stress over the lesion location. Preliminary results show that the range of stress over the breast surface was 1.23-5.84 kPa, the range over the lesion location 2.10-10.10 kPa, and the normalized stress 1.12-2.44 over the lesion location. Overall, the local stress over malignant lesions was higher than the average stress over the entire breast surface. This is the first step investigating criteria to distinguish between malignant and benign findings based upon clinical DBTMI data.

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Please use this url to cite or link to this publication:
author
; ; ; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Breast cancer screening, DBTMI, digital breast tomosynthesis, false positive findings, mechanical imaging
host publication
16th International Workshop on Breast Imaging, IWBI 2022
series title
Proceedings of SPIE - The International Society for Optical Engineering
editor
Bosmans, Hilde ; Marshall, Nicholas and Van Ongeval, Chantal
volume
12286
article number
1228607
publisher
SPIE
conference name
16th International Workshop on Breast Imaging, IWBI 2022
conference location
Leuven, Belgium
conference dates
2022-05-22 - 2022-05-25
external identifiers
  • scopus:85136084707
ISSN
1996-756X
0277-786X
ISBN
9781510655843
DOI
10.1117/12.2625715
language
English
LU publication?
yes
id
4469eb48-c421-4b20-97be-9ca4d3fdd2dd
date added to LUP
2022-10-06 14:10:39
date last changed
2024-06-14 22:42:38
@inproceedings{4469eb48-c421-4b20-97be-9ca4d3fdd2dd,
  abstract     = {{<p>We have developed a method for simultaneous tomosynthesis and mechanical imaging, called DBTMI. Mechanical imaging measures the stress distribution over the compressed breast surface. Malignant tissue is usually stiffer than benign, which results in higher stress on the compressed breast and enables to distinguish malignant from benign findings. By combining tomosynthesis and mechanical imaging, we could improve cancer detection accuracy by reducing the number of false positive findings. In this study we have analysed clinical DBTMI data, collected from 52 women from an ongoing pilot study at the Skåne University Hospital, Malmö, Sweden. We measured the range of the average stress over the breast surface, the range of average stress over the location of suspected lesions, and the normalized stress over the lesion location. Preliminary results show that the range of stress over the breast surface was 1.23-5.84 kPa, the range over the lesion location 2.10-10.10 kPa, and the normalized stress 1.12-2.44 over the lesion location. Overall, the local stress over malignant lesions was higher than the average stress over the entire breast surface. This is the first step investigating criteria to distinguish between malignant and benign findings based upon clinical DBTMI data. </p>}},
  author       = {{Axelsson, Rebecca and Dahlblom, Victor and Tingberg, Anders and Zackrisson, Sophia and Dustler, Magnus and Bakic, Predrag}},
  booktitle    = {{16th International Workshop on Breast Imaging, IWBI 2022}},
  editor       = {{Bosmans, Hilde and Marshall, Nicholas and Van Ongeval, Chantal}},
  isbn         = {{9781510655843}},
  issn         = {{1996-756X}},
  keywords     = {{Breast cancer screening; DBTMI; digital breast tomosynthesis; false positive findings; mechanical imaging}},
  language     = {{eng}},
  publisher    = {{SPIE}},
  series       = {{Proceedings of SPIE - The International Society for Optical Engineering}},
  title        = {{Simultaneous digital breast tomosynthesis and mechanical imaging in women recalled from screening - A preliminary analysis}},
  url          = {{http://dx.doi.org/10.1117/12.2625715}},
  doi          = {{10.1117/12.2625715}},
  volume       = {{12286}},
  year         = {{2022}},
}