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A genomic and historical synthesis of plague in 18th century Eurasia

Guellil, Meriam ; Kersten, Oliver ; Namouchi, Amine ; Luciani, Stefania ; Marota, Isolina ; Arcini, Caroline A. ; Iregren, Elisabeth LU ; Lindemann, Robert A. ; Warfvinge, Gunnar and Bakanidze, Lela , et al. (2020) In Proceedings of the National Academy of Sciences of the United States of America 117(45). p.28328-28335
Abstract

Plague continued to afflict Europe for more than five centuries after the Black Death. Yet, by the 17th century, the dynamics of plague had changed, leading to its slow decline in Western Europe over the subsequent 200 y, a period for which only one genome was previously available. Using a multidisciplinary approach, combining genomic and historical data, we assembled Y. pestis genomes from nine individuals covering four Eurasian sites and placed them into an historical context within the established phylogeny. CHE1 (Chechnya, Russia, 18th century) is now the latest Second Plague Pandemic genome and the first non-European sample in the post-Black Death lineage. Its placement in the phylogeny and our synthesis point toward the existence... (More)

Plague continued to afflict Europe for more than five centuries after the Black Death. Yet, by the 17th century, the dynamics of plague had changed, leading to its slow decline in Western Europe over the subsequent 200 y, a period for which only one genome was previously available. Using a multidisciplinary approach, combining genomic and historical data, we assembled Y. pestis genomes from nine individuals covering four Eurasian sites and placed them into an historical context within the established phylogeny. CHE1 (Chechnya, Russia, 18th century) is now the latest Second Plague Pandemic genome and the first non-European sample in the post-Black Death lineage. Its placement in the phylogeny and our synthesis point toward the existence of an extra-European reservoir feeding plague into Western Europe in multiple waves. By considering socioeconomic, ecological, and climatic factors we highlight the importance of a noneurocentric approach for the discussion on Second Plague Pandemic dynamics in Europe.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Yersinia pestis | ancient DNA | aDNA | pathogen | plague
in
Proceedings of the National Academy of Sciences of the United States of America
volume
117
issue
45
pages
8 pages
publisher
National Academy of Sciences
external identifiers
  • pmid:33106412
  • scopus:85096079818
ISSN
0027-8424
DOI
10.1073/pnas.2009677117
language
English
LU publication?
yes
id
4479569b-0438-43b3-bae4-dcc9a1b1e54a
date added to LUP
2021-01-15 12:56:20
date last changed
2024-04-18 01:09:21
@article{4479569b-0438-43b3-bae4-dcc9a1b1e54a,
  abstract     = {{<p>Plague continued to afflict Europe for more than five centuries after the Black Death. Yet, by the 17th century, the dynamics of plague had changed, leading to its slow decline in Western Europe over the subsequent 200 y, a period for which only one genome was previously available. Using a multidisciplinary approach, combining genomic and historical data, we assembled Y. pestis genomes from nine individuals covering four Eurasian sites and placed them into an historical context within the established phylogeny. CHE1 (Chechnya, Russia, 18th century) is now the latest Second Plague Pandemic genome and the first non-European sample in the post-Black Death lineage. Its placement in the phylogeny and our synthesis point toward the existence of an extra-European reservoir feeding plague into Western Europe in multiple waves. By considering socioeconomic, ecological, and climatic factors we highlight the importance of a noneurocentric approach for the discussion on Second Plague Pandemic dynamics in Europe.</p>}},
  author       = {{Guellil, Meriam and Kersten, Oliver and Namouchi, Amine and Luciani, Stefania and Marota, Isolina and Arcini, Caroline A. and Iregren, Elisabeth and Lindemann, Robert A. and Warfvinge, Gunnar and Bakanidze, Lela and Bitadze, Lia and Rubini, Mauro and Zaio, Paola and Zaio, Monica and Neri, Damiano and Stenseth, N. C. and Bramanti, Barbara}},
  issn         = {{0027-8424}},
  keywords     = {{Yersinia pestis | ancient DNA | aDNA | pathogen | plague}},
  language     = {{eng}},
  number       = {{45}},
  pages        = {{28328--28335}},
  publisher    = {{National Academy of Sciences}},
  series       = {{Proceedings of the National Academy of Sciences of the United States of America}},
  title        = {{A genomic and historical synthesis of plague in 18th century Eurasia}},
  url          = {{http://dx.doi.org/10.1073/pnas.2009677117}},
  doi          = {{10.1073/pnas.2009677117}},
  volume       = {{117}},
  year         = {{2020}},
}