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Agenesis of the ductus venosus and its correlation to hydrops fetalis and the fetal hepatic circulation: case reports and review of the literature.

Sivén, Maria ; Hägerstrand, Inga ; Ley, David LU and Svenningsen, Nils (1995) In Fetal and Pediatric Pathology 15(1). p.39-50
Abstract
Under normal conditions about 50% of the placental venous return bypasses the liver through the ductus venosus. This blood flow is preferentially directed toward the foramen ovale and provides optimum oxygenation to the fetal heart and brain. Absence of the ductus venosus is a rare vascular anomaly, the significance of which has been disputed. We distinguish the pattern in which the liver is entirely bypassed, a manifestation of a fundamental malformation in the umbilical venous system, from the pattern in which the ductus venosus is absent despite a normal course of the umbilical vein. We review the literature regarding the latter and report eight new cases. Three of the four previously reported cases showed associated malformations and... (More)
Under normal conditions about 50% of the placental venous return bypasses the liver through the ductus venosus. This blood flow is preferentially directed toward the foramen ovale and provides optimum oxygenation to the fetal heart and brain. Absence of the ductus venosus is a rare vascular anomaly, the significance of which has been disputed. We distinguish the pattern in which the liver is entirely bypassed, a manifestation of a fundamental malformation in the umbilical venous system, from the pattern in which the ductus venosus is absent despite a normal course of the umbilical vein. We review the literature regarding the latter and report eight new cases. Three of the four previously reported cases showed associated malformations and two of them suffered from portal congestion and hydrops. Among our eight cases three showed severe malformations in the cardiovascular system. Three cases presented themselves with hydrops fetalis and disturbance in the portal circulation, and two case (Less)
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
portal hypertension, malformation, ductus venosus, hydrops fetalis
in
Fetal and Pediatric Pathology
volume
15
issue
1
pages
39 - 50
publisher
Taylor & Francis
external identifiers
  • scopus:0029039941
ISSN
1551-3823
DOI
10.3109/15513819509026938
language
English
LU publication?
yes
id
447eeb68-82ee-4a27-a2c6-ca037ec9e0ed (old id 1109493)
date added to LUP
2016-04-01 12:32:28
date last changed
2021-04-04 06:05:35
@article{447eeb68-82ee-4a27-a2c6-ca037ec9e0ed,
  abstract     = {{Under normal conditions about 50% of the placental venous return bypasses the liver through the ductus venosus. This blood flow is preferentially directed toward the foramen ovale and provides optimum oxygenation to the fetal heart and brain. Absence of the ductus venosus is a rare vascular anomaly, the significance of which has been disputed. We distinguish the pattern in which the liver is entirely bypassed, a manifestation of a fundamental malformation in the umbilical venous system, from the pattern in which the ductus venosus is absent despite a normal course of the umbilical vein. We review the literature regarding the latter and report eight new cases. Three of the four previously reported cases showed associated malformations and two of them suffered from portal congestion and hydrops. Among our eight cases three showed severe malformations in the cardiovascular system. Three cases presented themselves with hydrops fetalis and disturbance in the portal circulation, and two case}},
  author       = {{Sivén, Maria and Hägerstrand, Inga and Ley, David and Svenningsen, Nils}},
  issn         = {{1551-3823}},
  keywords     = {{portal hypertension; malformation; ductus venosus; hydrops fetalis}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{39--50}},
  publisher    = {{Taylor & Francis}},
  series       = {{Fetal and Pediatric Pathology}},
  title        = {{Agenesis of the ductus venosus and its correlation to hydrops fetalis and the fetal hepatic circulation: case reports and review of the literature.}},
  url          = {{http://dx.doi.org/10.3109/15513819509026938}},
  doi          = {{10.3109/15513819509026938}},
  volume       = {{15}},
  year         = {{1995}},
}