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Prevalence and molecular epidemiology of Staphylococcus aureus in Swedish nursing homes-as revealed in the SHADES study dagger

Stark, L.; Olofsson, M.; Lofgren, S.; Mölstad, Sigvard LU ; Lindgren, P. -E. and Matussek, A. (2014) In Epidemiology and Infection 142(6). p.1310-1316
Abstract
Knowledge of carriage and population dynamics of Staphylococcus aureus is crucial for infection risk assessment and to reveal transmission patterns of strains. We report the prevalence and molecular epidemiology of S. aureus in elderly people (n=290) living in nursing homes in three cities in the south of Sweden. The overall carriage prevalence rate was 48% when results from nares (31%) and throat (34%) samples were combined. Common spa types were equally distributed but a frequent type, t160, was found only in one of the regions. Carriage of different spa types was detected in 23% of individuals and antimicrobial resistance rates were higher in S. aureus isolates from those carrying more than one spa type. Five of the 21 individuals who... (More)
Knowledge of carriage and population dynamics of Staphylococcus aureus is crucial for infection risk assessment and to reveal transmission patterns of strains. We report the prevalence and molecular epidemiology of S. aureus in elderly people (n=290) living in nursing homes in three cities in the south of Sweden. The overall carriage prevalence rate was 48% when results from nares (31%) and throat (34%) samples were combined. Common spa types were equally distributed but a frequent type, t160, was found only in one of the regions. Carriage of different spa types was detected in 23% of individuals and antimicrobial resistance rates were higher in S. aureus isolates from those carrying more than one spa type. Five of the 21 individuals who carried different spa types were colonized simultaneously with resistant and non-resistant strains. Seventeen per cent of the individuals carried S. aureus of the same spa type on all occasions. Methicillin resistance was not detected. In conclusion we found a high prevalence of S. aureus in this elderly population with a high rate of dual colonization with different spa types. We also found signs of institutional spread of one strain. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Colonization, molecular typing, spa type, multiclonality, nursing home
in
Epidemiology and Infection
volume
142
issue
6
pages
1310 - 1316
publisher
Cambridge University Press
external identifiers
  • wos:000334247600020
  • scopus:84898639805
ISSN
0950-2688
DOI
10.1017/S0950268813002033
language
English
LU publication?
yes
id
16abd945-3ba0-4354-a7be-dc57f7a6a898 (old id 4487844)
date added to LUP
2014-07-01 07:33:27
date last changed
2017-01-01 03:30:01
@article{16abd945-3ba0-4354-a7be-dc57f7a6a898,
  abstract     = {Knowledge of carriage and population dynamics of Staphylococcus aureus is crucial for infection risk assessment and to reveal transmission patterns of strains. We report the prevalence and molecular epidemiology of S. aureus in elderly people (n=290) living in nursing homes in three cities in the south of Sweden. The overall carriage prevalence rate was 48% when results from nares (31%) and throat (34%) samples were combined. Common spa types were equally distributed but a frequent type, t160, was found only in one of the regions. Carriage of different spa types was detected in 23% of individuals and antimicrobial resistance rates were higher in S. aureus isolates from those carrying more than one spa type. Five of the 21 individuals who carried different spa types were colonized simultaneously with resistant and non-resistant strains. Seventeen per cent of the individuals carried S. aureus of the same spa type on all occasions. Methicillin resistance was not detected. In conclusion we found a high prevalence of S. aureus in this elderly population with a high rate of dual colonization with different spa types. We also found signs of institutional spread of one strain.},
  author       = {Stark, L. and Olofsson, M. and Lofgren, S. and Mölstad, Sigvard and Lindgren, P. -E. and Matussek, A.},
  issn         = {0950-2688},
  keyword      = {Colonization,molecular typing,spa type,multiclonality,nursing home},
  language     = {eng},
  number       = {6},
  pages        = {1310--1316},
  publisher    = {Cambridge University Press},
  series       = {Epidemiology and Infection},
  title        = {Prevalence and molecular epidemiology of Staphylococcus aureus in Swedish nursing homes-as revealed in the SHADES study dagger},
  url          = {http://dx.doi.org/10.1017/S0950268813002033},
  volume       = {142},
  year         = {2014},
}