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Diffusion MRI acquisition for tractography : Diffusion sequences

Campbell, Jennifer S.W. ; Baete, Steven H. ; Cohen-Adad, Julien ; Tournier, J. Donald ; Szczepankiewicz, Filip LU orcid ; Beaulieu, Christian ; Baron, Corey A. ; Mani, Merry ; Setsompop, Kawin and Liao, Congyu , et al. (2024) p.123-141
Abstract

This is the second of three chapters on diffusion MRI acquisition for tractography. This chapter covers image formation, which is largely independent of the creation of diffusion contrast (Chapter 6). The Stejskal-Tanner diffusion experiments in the 1960s were bulk NMR measurements of diffusion; the addition of spatial localization, i.e., imaging, would follow decades later. The excitation and readout should maximize the sensitivity and efficiency of diffusion encoding. This chapter first covers diffusion image formation through the commonly used single-shot echo planar imaging (EPI) technique and variants. Imaging parameter choices—voxel size and shape, bandwidth, sequence timing, and phase encoding direction—are discussed. The chapter... (More)

This is the second of three chapters on diffusion MRI acquisition for tractography. This chapter covers image formation, which is largely independent of the creation of diffusion contrast (Chapter 6). The Stejskal-Tanner diffusion experiments in the 1960s were bulk NMR measurements of diffusion; the addition of spatial localization, i.e., imaging, would follow decades later. The excitation and readout should maximize the sensitivity and efficiency of diffusion encoding. This chapter first covers diffusion image formation through the commonly used single-shot echo planar imaging (EPI) technique and variants. Imaging parameter choices—voxel size and shape, bandwidth, sequence timing, and phase encoding direction—are discussed. The chapter then moves on to reduced sampling schemes: in-plane parallel imaging and phase partial Fourier acquisition, followed by methods for segmentation of multishot diffusion acquisition. Next, volumetric acquisition and through-plane acceleration (simultaneous multislice and multislab acquisition) are introduced. A discussion of artifacts that can be mitigated by changes to the imaging part of the acquisition follows. The chapter concludes with a consideration of the effect of sequence timing (TE, TR) and preparation blocks on the image contrast, and considerations for the choice of spatial and angular resolution.

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organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Artifact reduction, Diffusion, MRI acquisition, Segmented diffusion sequences, Single-shot diffusion sequences, Tractography
host publication
Handbook of Diffusion MR Tractography : Imaging Methods, Biophysical Models, Algorithms and Applications - Imaging Methods, Biophysical Models, Algorithms and Applications
pages
19 pages
publisher
Elsevier
external identifiers
  • scopus:85218396649
ISBN
9780128188958
9780128188941
DOI
10.1016/B978-0-12-818894-1.00019-7
language
English
LU publication?
yes
id
44e1e6c4-6f91-4c47-a9e9-c6b4953896a8
date added to LUP
2025-06-05 10:49:24
date last changed
2025-08-28 18:22:59
@inbook{44e1e6c4-6f91-4c47-a9e9-c6b4953896a8,
  abstract     = {{<p>This is the second of three chapters on diffusion MRI acquisition for tractography. This chapter covers image formation, which is largely independent of the creation of diffusion contrast (Chapter 6). The Stejskal-Tanner diffusion experiments in the 1960s were bulk NMR measurements of diffusion; the addition of spatial localization, i.e., imaging, would follow decades later. The excitation and readout should maximize the sensitivity and efficiency of diffusion encoding. This chapter first covers diffusion image formation through the commonly used single-shot echo planar imaging (EPI) technique and variants. Imaging parameter choices—voxel size and shape, bandwidth, sequence timing, and phase encoding direction—are discussed. The chapter then moves on to reduced sampling schemes: in-plane parallel imaging and phase partial Fourier acquisition, followed by methods for segmentation of multishot diffusion acquisition. Next, volumetric acquisition and through-plane acceleration (simultaneous multislice and multislab acquisition) are introduced. A discussion of artifacts that can be mitigated by changes to the imaging part of the acquisition follows. The chapter concludes with a consideration of the effect of sequence timing (TE, TR) and preparation blocks on the image contrast, and considerations for the choice of spatial and angular resolution.</p>}},
  author       = {{Campbell, Jennifer S.W. and Baete, Steven H. and Cohen-Adad, Julien and Tournier, J. Donald and Szczepankiewicz, Filip and Beaulieu, Christian and Baron, Corey A. and Mani, Merry and Setsompop, Kawin and Liao, Congyu and Tardif, Christine L. and Vos, Sjoerd B. and Yendiki, Anastasia and Leppert, Ilana R. and Fieremans, Els and Pike, G. Bruce}},
  booktitle    = {{Handbook of Diffusion MR Tractography : Imaging Methods, Biophysical Models, Algorithms and Applications}},
  isbn         = {{9780128188958}},
  keywords     = {{Artifact reduction; Diffusion; MRI acquisition; Segmented diffusion sequences; Single-shot diffusion sequences; Tractography}},
  language     = {{eng}},
  pages        = {{123--141}},
  publisher    = {{Elsevier}},
  title        = {{Diffusion MRI acquisition for tractography : Diffusion sequences}},
  url          = {{http://dx.doi.org/10.1016/B978-0-12-818894-1.00019-7}},
  doi          = {{10.1016/B978-0-12-818894-1.00019-7}},
  year         = {{2024}},
}