Exclusion of Disperse Orange 3 is possible from the textile dye mix present in the Swedish baseline patch test series. A study by the Swedish Contact Dermatitis Research Group
(2023) In Contact Dermatitis 88(1). p.54-59- Abstract
Background: The textile dye mix (TDM) 6.6% in petrolatum contains Disperse Blue (DB) 35, Disperse Yellow 3, Disperse Orange (DO) 1 and 3, Disperse Red 1 and 17, and DB 106 and 124. The most frequent allergen in TDM-positive patients is DO 3. Around 85% of para-phenylenediamine (PPD)-allergic dermatitis patients have been positive to DO 3. There has been a discussion to exclude DO 3 from TDM 6.6% because of strong simultaneous reactions to TDM and PPD. Objectives: To study if DO 3 can be excluded from TDM 6.6%. Methods: Patch tests were performed on 1481 dermatitis patients with TDM 6.6%, TDM 7.0% (without DO 3 but the other disperse dyes at 1.0% each), DO 3 1.0%, and PPD 1.0% pet. Results: Contact allergy to TDM 6.6% was 3.6% and to TDM... (More)
Background: The textile dye mix (TDM) 6.6% in petrolatum contains Disperse Blue (DB) 35, Disperse Yellow 3, Disperse Orange (DO) 1 and 3, Disperse Red 1 and 17, and DB 106 and 124. The most frequent allergen in TDM-positive patients is DO 3. Around 85% of para-phenylenediamine (PPD)-allergic dermatitis patients have been positive to DO 3. There has been a discussion to exclude DO 3 from TDM 6.6% because of strong simultaneous reactions to TDM and PPD. Objectives: To study if DO 3 can be excluded from TDM 6.6%. Methods: Patch tests were performed on 1481 dermatitis patients with TDM 6.6%, TDM 7.0% (without DO 3 but the other disperse dyes at 1.0% each), DO 3 1.0%, and PPD 1.0% pet. Results: Contact allergy to TDM 6.6% was 3.6% and to TDM 7.0% was 3.0%. All 26 DO 3-positive patients were positive to PPD. The 44 patients positive to TDM 7.0% plus the 13 positive to PPD and TDM 6.6% but negative to TDM 7.0% were 57, outnumbering the 53 positive to TDM 6.6%. Conclusion: TDM 7.0% can replace TDM 6.6% in the Swedish baseline series, since TDM 7.0% together with PPD 1.0% will detect patients with textile dye allergy.
(Less)
- author
- organization
- publishing date
- 2023
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- allergic contact dermatitis, contact allergy, delayed hypersensitivity, disperse dyes, patch testing, textile dermatitis
- in
- Contact Dermatitis
- volume
- 88
- issue
- 1
- pages
- 54 - 59
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85139259115
- pmid:36112512
- ISSN
- 0105-1873
- DOI
- 10.1111/cod.14223
- language
- English
- LU publication?
- yes
- id
- 44f2c54f-229b-4e4f-9e97-462be92a965f
- date added to LUP
- 2022-12-19 15:18:50
- date last changed
- 2024-06-27 23:12:54
@article{44f2c54f-229b-4e4f-9e97-462be92a965f, abstract = {{<p>Background: The textile dye mix (TDM) 6.6% in petrolatum contains Disperse Blue (DB) 35, Disperse Yellow 3, Disperse Orange (DO) 1 and 3, Disperse Red 1 and 17, and DB 106 and 124. The most frequent allergen in TDM-positive patients is DO 3. Around 85% of para-phenylenediamine (PPD)-allergic dermatitis patients have been positive to DO 3. There has been a discussion to exclude DO 3 from TDM 6.6% because of strong simultaneous reactions to TDM and PPD. Objectives: To study if DO 3 can be excluded from TDM 6.6%. Methods: Patch tests were performed on 1481 dermatitis patients with TDM 6.6%, TDM 7.0% (without DO 3 but the other disperse dyes at 1.0% each), DO 3 1.0%, and PPD 1.0% pet. Results: Contact allergy to TDM 6.6% was 3.6% and to TDM 7.0% was 3.0%. All 26 DO 3-positive patients were positive to PPD. The 44 patients positive to TDM 7.0% plus the 13 positive to PPD and TDM 6.6% but negative to TDM 7.0% were 57, outnumbering the 53 positive to TDM 6.6%. Conclusion: TDM 7.0% can replace TDM 6.6% in the Swedish baseline series, since TDM 7.0% together with PPD 1.0% will detect patients with textile dye allergy.</p>}}, author = {{Isaksson, Marléne and Antelmi, Annarita and Dahlin, Jakob and Stenton, Joanna and Svedman, Cecilia and Zimerson, Erik and Glas, Bo and Hagvall, Lina and Lagrelius, Maria and Löwnertz, Anna and Malinauskiene, Laura and Matura, Mihaly and Bruze, Magnus}}, issn = {{0105-1873}}, keywords = {{allergic contact dermatitis; contact allergy; delayed hypersensitivity; disperse dyes; patch testing; textile dermatitis}}, language = {{eng}}, number = {{1}}, pages = {{54--59}}, publisher = {{Wiley-Blackwell}}, series = {{Contact Dermatitis}}, title = {{Exclusion of Disperse Orange 3 is possible from the textile dye mix present in the Swedish baseline patch test series. A study by the Swedish Contact Dermatitis Research Group}}, url = {{http://dx.doi.org/10.1111/cod.14223}}, doi = {{10.1111/cod.14223}}, volume = {{88}}, year = {{2023}}, }