Saccharomyces cerevisiae: a potential host for carboxylic acid production from lignocellulosic feedstock?
(2014) In Applied Microbiology and Biotechnology 98(17). p.7299-7318- Abstract
- Carboxylic acids are important bulk chemicals that can be used as building blocks for the production of polymers, as acidulants, preservatives and flavour compound or as precursors for the synthesis of pharmaceuticals. Today, their production mainly takes place through catalytic processing of petroleum-based precursors. An appealing alternative would be to produce these compounds from renewable resources, using tailor-made microorganisms. Saccharomyces cerevisiae has already demonstrated its value for bioethanol production from renewable resources. In this review, we discuss Saccharomyces cerevisiae engineering potential, current strategies for carboxylic acid production as well as the specific challenges linked to the use of... (More)
- Carboxylic acids are important bulk chemicals that can be used as building blocks for the production of polymers, as acidulants, preservatives and flavour compound or as precursors for the synthesis of pharmaceuticals. Today, their production mainly takes place through catalytic processing of petroleum-based precursors. An appealing alternative would be to produce these compounds from renewable resources, using tailor-made microorganisms. Saccharomyces cerevisiae has already demonstrated its value for bioethanol production from renewable resources. In this review, we discuss Saccharomyces cerevisiae engineering potential, current strategies for carboxylic acid production as well as the specific challenges linked to the use of lignocellulosic biomass as carbon source. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4526700
- author
- Sandström, Anders LU ; Almqvist, Henrik LU ; Nunes, Diogo JP LU ; Neves, Dário ; Lidén, Gunnar LU and Gorwa-Grauslund, Marie-Francoise LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Applied Microbiology and Biotechnology
- volume
- 98
- issue
- 17
- pages
- 7299 - 7318
- publisher
- Springer
- external identifiers
-
- pmid:24970456
- wos:000340837600002
- scopus:84906948968
- pmid:24970456
- ISSN
- 1432-0614
- DOI
- 10.1007/s00253-014-5866-5
- language
- English
- LU publication?
- yes
- id
- 2f1f911a-be78-4223-8815-6ba73207cda8 (old id 4526700)
- date added to LUP
- 2016-04-01 10:52:50
- date last changed
- 2023-11-24 20:28:30
@article{2f1f911a-be78-4223-8815-6ba73207cda8, abstract = {{Carboxylic acids are important bulk chemicals that can be used as building blocks for the production of polymers, as acidulants, preservatives and flavour compound or as precursors for the synthesis of pharmaceuticals. Today, their production mainly takes place through catalytic processing of petroleum-based precursors. An appealing alternative would be to produce these compounds from renewable resources, using tailor-made microorganisms. Saccharomyces cerevisiae has already demonstrated its value for bioethanol production from renewable resources. In this review, we discuss Saccharomyces cerevisiae engineering potential, current strategies for carboxylic acid production as well as the specific challenges linked to the use of lignocellulosic biomass as carbon source.}}, author = {{Sandström, Anders and Almqvist, Henrik and Nunes, Diogo JP and Neves, Dário and Lidén, Gunnar and Gorwa-Grauslund, Marie-Francoise}}, issn = {{1432-0614}}, language = {{eng}}, number = {{17}}, pages = {{7299--7318}}, publisher = {{Springer}}, series = {{Applied Microbiology and Biotechnology}}, title = {{Saccharomyces cerevisiae: a potential host for carboxylic acid production from lignocellulosic feedstock?}}, url = {{http://dx.doi.org/10.1007/s00253-014-5866-5}}, doi = {{10.1007/s00253-014-5866-5}}, volume = {{98}}, year = {{2014}}, }