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The importance of being specific-a meta-analysis evaluating the effect of antibiotics in acute otitis media.

Gisselsson-Solén, Marie LU (2014) In International Journal of Pediatric Otorhinolaryngology 78(8). p.1221-1227
Abstract
Whether acute otitis media (AOM) should be the cause for antibiotic treatment has been a matter of debate during the last decades. Treatment guidelines are based on less than twenty trials that have found the effect of antibiotics on symptomatic outcomes in AOM, such as pain, to be very modest. Two recent trials found a more substantial effect of antibiotics when they looked at treatment failure as the outcome. That the effect varies with the chosen outcome may not only be because the true effect is different but also because different outcomes are more or less specific for the disease in question.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
International Journal of Pediatric Otorhinolaryngology
volume
78
issue
8
pages
1221 - 1227
publisher
Elsevier
external identifiers
  • pmid:24948134
  • wos:000340304800004
  • scopus:84904055073
ISSN
1872-8464
DOI
10.1016/j.ijporl.2014.05.029
language
English
LU publication?
yes
id
e41bc8f8-f6cb-4363-95b0-4e0d05cae9f3 (old id 4527864)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24948134?dopt=Abstract
date added to LUP
2014-07-06 19:19:19
date last changed
2017-01-01 04:15:40
@article{e41bc8f8-f6cb-4363-95b0-4e0d05cae9f3,
  abstract     = {Whether acute otitis media (AOM) should be the cause for antibiotic treatment has been a matter of debate during the last decades. Treatment guidelines are based on less than twenty trials that have found the effect of antibiotics on symptomatic outcomes in AOM, such as pain, to be very modest. Two recent trials found a more substantial effect of antibiotics when they looked at treatment failure as the outcome. That the effect varies with the chosen outcome may not only be because the true effect is different but also because different outcomes are more or less specific for the disease in question.},
  author       = {Gisselsson-Solén, Marie},
  issn         = {1872-8464},
  language     = {eng},
  number       = {8},
  pages        = {1221--1227},
  publisher    = {Elsevier},
  series       = {International Journal of Pediatric Otorhinolaryngology},
  title        = {The importance of being specific-a meta-analysis evaluating the effect of antibiotics in acute otitis media.},
  url          = {http://dx.doi.org/10.1016/j.ijporl.2014.05.029},
  volume       = {78},
  year         = {2014},
}