Home treatment of patients with small to medium sized acute pulmonary embolism.
Elf, Johan LU ; Jögi, Jonas LU
and Bajc, Marika
LU
(2015)
In Journal of Thrombosis and Thrombolysis
39(2).
p.166-172
- Abstract
- Most patients with acute pulmonary embolism (PE) are still treated as inpatients. This is a retrospective cohort study of patients with acute PE, diagnosed using V/P SPECT between 2007 and 2011. Patients were treated at home if they were hemodynamically stable, did not require oxygen or parenteral analgetics, had no contraindications to anticoagulant treatment and V/P SPECT showed an extension of the PE of less than 40 %. The aim of the study was to evaluate the efficacy and safety of home treatment with our algorithm. During the study period 416 outpatients were diagnosed with acute symptomatic PE of whom in total 260 (62.5 %) were discharged home from the emergency unit and another 47 (11 %) within 24 h from admission. During 3 months... (More)
- Most patients with acute pulmonary embolism (PE) are still treated as inpatients. This is a retrospective cohort study of patients with acute PE, diagnosed using V/P SPECT between 2007 and 2011. Patients were treated at home if they were hemodynamically stable, did not require oxygen or parenteral analgetics, had no contraindications to anticoagulant treatment and V/P SPECT showed an extension of the PE of less than 40 %. The aim of the study was to evaluate the efficacy and safety of home treatment with our algorithm. During the study period 416 outpatients were diagnosed with acute symptomatic PE of whom in total 260 (62.5 %) were discharged home from the emergency unit and another 47 (11 %) within 24 h from admission. During 3 months follow-up one (0.3 %) patient had a recurrent thrombotic event. Eleven (3.6 %) patients had a major or clinically relevant bleed and the overall mortality was 2 % (n = 6). There were no PE-related mortality. Home treatment should be considered and is safe in the majority of hemodynamically stable outpatients with small to medium size PE, quantified using V/P SPECT. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4528192
- author
- Elf, Johan
LU
; Jögi, Jonas
LU
and Bajc, Marika
LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Thrombosis and Thrombolysis
- volume
- 39
- issue
- 2
- pages
- 166 - 172
- publisher
- Springer
- external identifiers
-
- pmid:24942995
- wos:000349528100003
- scopus:84939885117
- pmid:24942995
- ISSN
- 1573-742X
- DOI
- 10.1007/s11239-014-1097-y
- language
- English
- LU publication?
- yes
- id
- e9225d09-940a-4775-9f4d-0e980c5be34b (old id 4528192)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24942995?dopt=Abstract
- date added to LUP
- 2016-04-01 10:13:28
- date last changed
- 2022-02-17 07:53:53
@article{e9225d09-940a-4775-9f4d-0e980c5be34b,
abstract = {{Most patients with acute pulmonary embolism (PE) are still treated as inpatients. This is a retrospective cohort study of patients with acute PE, diagnosed using V/P SPECT between 2007 and 2011. Patients were treated at home if they were hemodynamically stable, did not require oxygen or parenteral analgetics, had no contraindications to anticoagulant treatment and V/P SPECT showed an extension of the PE of less than 40 %. The aim of the study was to evaluate the efficacy and safety of home treatment with our algorithm. During the study period 416 outpatients were diagnosed with acute symptomatic PE of whom in total 260 (62.5 %) were discharged home from the emergency unit and another 47 (11 %) within 24 h from admission. During 3 months follow-up one (0.3 %) patient had a recurrent thrombotic event. Eleven (3.6 %) patients had a major or clinically relevant bleed and the overall mortality was 2 % (n = 6). There were no PE-related mortality. Home treatment should be considered and is safe in the majority of hemodynamically stable outpatients with small to medium size PE, quantified using V/P SPECT.}},
author = {{Elf, Johan and Jögi, Jonas and Bajc, Marika}},
issn = {{1573-742X}},
language = {{eng}},
number = {{2}},
pages = {{166--172}},
publisher = {{Springer}},
series = {{Journal of Thrombosis and Thrombolysis}},
title = {{Home treatment of patients with small to medium sized acute pulmonary embolism.}},
url = {{http://dx.doi.org/10.1007/s11239-014-1097-y}},
doi = {{10.1007/s11239-014-1097-y}},
volume = {{39}},
year = {{2015}},
}