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Breast cancer detection in digital breast tomosynthesis and digital mammography - A side-by-side review of discrepant cases.

Lång, Kristina LU ; Andersson, Ingvar LU and Zackrisson, Sophia LU (2014) In British Journal of Radiology 87(1040).
Abstract
Objective: To analyse discrepant breast cancer detection in digital breast tomosynthesis (DBT) and digital mammography (DM). Methods: From a previous detection study comparing DBT and DM, 26 discrepant cases were extracted, 19 detected by DBT only and 7 by DM only. An expert panel of 3 radiologists reviewed these cases and documented level of discrepancy, lesion visibility, radiographic pattern, lesion conspicuity and assessed the reason for non-detection. Differences between groups were tested using the Wilcoxon Rank Sum test, the Kruskal-Wallis test and visual grading characteristics. Results: The proportion of lesion periphery in fatty tissue was statistically significantly larger, and there were significantly more spiculated masses in... (More)
Objective: To analyse discrepant breast cancer detection in digital breast tomosynthesis (DBT) and digital mammography (DM). Methods: From a previous detection study comparing DBT and DM, 26 discrepant cases were extracted, 19 detected by DBT only and 7 by DM only. An expert panel of 3 radiologists reviewed these cases and documented level of discrepancy, lesion visibility, radiographic pattern, lesion conspicuity and assessed the reason for non-detection. Differences between groups were tested using the Wilcoxon Rank Sum test, the Kruskal-Wallis test and visual grading characteristics. Results: The proportion of lesion periphery in fatty tissue was statistically significantly larger, and there were significantly more spiculated masses in DBT compared to DM in the DBT Only group (p=0.018; p=0.015). The main reasons for missing a lesion were poor lesion visibility when using DM and interpretative error when using DBT. Conclusion: Lesion visualization is superior with DBT, particularly of spiculated tumours. A major reason for non-detection in DBT seems to be interpretative error, which may be due to lack of experience. (Less)
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Contribution to journal
publication status
published
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in
British Journal of Radiology
volume
87
issue
1040
publisher
British Inst Radiology
external identifiers
  • pmid:24896197
  • wos:000339419800010
  • scopus:84907487498
ISSN
1748-880X
DOI
10.1259/bjr.20140080
language
English
LU publication?
yes
id
484b4418-696e-42fe-8529-b0eed7f52b58 (old id 4529274)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24896197?dopt=Abstract
date added to LUP
2014-07-04 14:53:05
date last changed
2017-09-24 03:06:53
@article{484b4418-696e-42fe-8529-b0eed7f52b58,
  abstract     = {Objective: To analyse discrepant breast cancer detection in digital breast tomosynthesis (DBT) and digital mammography (DM). Methods: From a previous detection study comparing DBT and DM, 26 discrepant cases were extracted, 19 detected by DBT only and 7 by DM only. An expert panel of 3 radiologists reviewed these cases and documented level of discrepancy, lesion visibility, radiographic pattern, lesion conspicuity and assessed the reason for non-detection. Differences between groups were tested using the Wilcoxon Rank Sum test, the Kruskal-Wallis test and visual grading characteristics. Results: The proportion of lesion periphery in fatty tissue was statistically significantly larger, and there were significantly more spiculated masses in DBT compared to DM in the DBT Only group (p=0.018; p=0.015). The main reasons for missing a lesion were poor lesion visibility when using DM and interpretative error when using DBT. Conclusion: Lesion visualization is superior with DBT, particularly of spiculated tumours. A major reason for non-detection in DBT seems to be interpretative error, which may be due to lack of experience.},
  articleno    = {20140080},
  author       = {Lång, Kristina and Andersson, Ingvar and Zackrisson, Sophia},
  issn         = {1748-880X},
  language     = {eng},
  number       = {1040},
  publisher    = {British Inst Radiology},
  series       = {British Journal of Radiology},
  title        = {Breast cancer detection in digital breast tomosynthesis and digital mammography - A side-by-side review of discrepant cases.},
  url          = {http://dx.doi.org/10.1259/bjr.20140080},
  volume       = {87},
  year         = {2014},
}