Cardiovascular consequences of a polygenetic component of blood pressure in an urban-based longitudinal study: the Malmö Diet and Cancer.
Fava, Cristiano LU ; Ohlsson, Therese ; Sjögren, Marketa LU ; Tagetti, Angela ; Almgren, Peter LU ; Engström, Gunnar LU ; Nilsson, Peter LU ; Hedblad, Bo LU ; Minuz, Pietro and Melander, Olle LU
(2014)
In Journal of Hypertension
32(7).
p.1424-1428
- Abstract
- A recently published genome wide association study identified 29 single nucleotide polymorphisms (SNPs) influencing blood pressure (BP). Case-control studies suggest that a genetic risk score (GRS) based on these 29 SNPs affect the risk of cardiovascular disease (CVD), but its role for CVD at population level is unknown. Here, we prospectively evaluate the impact of this polygenetic BP component on CVD morbidity and mortality in a large urban-based middle-aged population.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4529603
- author
- Fava, Cristiano
LU
; Ohlsson, Therese
; Sjögren, Marketa
LU
; Tagetti, Angela
; Almgren, Peter
LU
; Engström, Gunnar
LU
; Nilsson, Peter
LU
; Hedblad, Bo
LU
; Minuz, Pietro
and Melander, Olle
LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Hypertension
- volume
- 32
- issue
- 7
- pages
- 1424 - 1428
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- pmid:24879493
- wos:000337351400012
- scopus:84903888344
- ISSN
- 1473-5598
- DOI
- 10.1097/HJH.0000000000000209
- project
- Genetic causes and prediction of hypertension
- language
- English
- LU publication?
- yes
- id
- 638c3a9c-fd6b-44cc-922f-797d1f6d0e2c (old id 4529603)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24879493?dopt=Abstract
- date added to LUP
- 2016-04-01 09:55:52
- date last changed
- 2024-03-14 02:48:53
@article{638c3a9c-fd6b-44cc-922f-797d1f6d0e2c,
abstract = {{A recently published genome wide association study identified 29 single nucleotide polymorphisms (SNPs) influencing blood pressure (BP). Case-control studies suggest that a genetic risk score (GRS) based on these 29 SNPs affect the risk of cardiovascular disease (CVD), but its role for CVD at population level is unknown. Here, we prospectively evaluate the impact of this polygenetic BP component on CVD morbidity and mortality in a large urban-based middle-aged population.}},
author = {{Fava, Cristiano and Ohlsson, Therese and Sjögren, Marketa and Tagetti, Angela and Almgren, Peter and Engström, Gunnar and Nilsson, Peter and Hedblad, Bo and Minuz, Pietro and Melander, Olle}},
issn = {{1473-5598}},
language = {{eng}},
number = {{7}},
pages = {{1424--1428}},
publisher = {{Lippincott Williams & Wilkins}},
series = {{Journal of Hypertension}},
title = {{Cardiovascular consequences of a polygenetic component of blood pressure in an urban-based longitudinal study: the Malmö Diet and Cancer.}},
url = {{http://dx.doi.org/10.1097/HJH.0000000000000209}},
doi = {{10.1097/HJH.0000000000000209}},
volume = {{32}},
year = {{2014}},
}