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Barrier-enforcing measures as treatment principle in allergic rhinitis: a systematic review

Andersson, Morgan LU ; Greiff, Lennart LU ; Ojeda, Pedro and Wollmer, Per LU (2014) In Current Medical Research and Opinion 30(6). p.1131-1137
Abstract
Background and objectives Barrier-enforcing measures have been suggested as treatment options for allergic rhinitis. This review identifies and describes the literature on the subject. Methods Relevant publications were searched for in the PubMed database (search entries: 'allergic rhinitis' and 'treatment'). The evaluation comprised condition (seasonal or perennial allergic rhinitis), type of intervention, duration of treatment, study design, peer review status or not, number of test subjects, type of allergen exposure, and outcome in terms of effects or not on nasal symptoms of allergic rhinitis. Results Fifteen studies were either identified in the PubMed database search or from the reference lists of identified publications. Seven were... (More)
Background and objectives Barrier-enforcing measures have been suggested as treatment options for allergic rhinitis. This review identifies and describes the literature on the subject. Methods Relevant publications were searched for in the PubMed database (search entries: 'allergic rhinitis' and 'treatment'). The evaluation comprised condition (seasonal or perennial allergic rhinitis), type of intervention, duration of treatment, study design, peer review status or not, number of test subjects, type of allergen exposure, and outcome in terms of effects or not on nasal symptoms of allergic rhinitis. Results Fifteen studies were either identified in the PubMed database search or from the reference lists of identified publications. Seven were placebo-controlled, randomized, and peer-reviewed, and symptom-reducing effects were reported by all of these reports. Limitations of this review reflect that the remainder of the studies had inferior designs, particularly lack of placebo control. Conclusions Barrier-enforcing measures as achieved by nasal administrations of cellulose powder and microemulsions, respectively, have symptom-reducing effects in allergic rhinitis. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Allergy, Microemulsion, Treatment
in
Current Medical Research and Opinion
volume
30
issue
6
pages
1131 - 1137
publisher
LibraPharm
external identifiers
  • wos:000336499400018
  • scopus:84900833308
ISSN
1473-4877
DOI
10.1185/03007995.2014.882299
language
English
LU publication?
yes
id
a84fb70b-ddbb-49f5-9666-de4a9744eb02 (old id 4552429)
date added to LUP
2014-08-01 07:38:30
date last changed
2017-10-22 03:01:40
@article{a84fb70b-ddbb-49f5-9666-de4a9744eb02,
  abstract     = {Background and objectives Barrier-enforcing measures have been suggested as treatment options for allergic rhinitis. This review identifies and describes the literature on the subject. Methods Relevant publications were searched for in the PubMed database (search entries: 'allergic rhinitis' and 'treatment'). The evaluation comprised condition (seasonal or perennial allergic rhinitis), type of intervention, duration of treatment, study design, peer review status or not, number of test subjects, type of allergen exposure, and outcome in terms of effects or not on nasal symptoms of allergic rhinitis. Results Fifteen studies were either identified in the PubMed database search or from the reference lists of identified publications. Seven were placebo-controlled, randomized, and peer-reviewed, and symptom-reducing effects were reported by all of these reports. Limitations of this review reflect that the remainder of the studies had inferior designs, particularly lack of placebo control. Conclusions Barrier-enforcing measures as achieved by nasal administrations of cellulose powder and microemulsions, respectively, have symptom-reducing effects in allergic rhinitis.},
  author       = {Andersson, Morgan and Greiff, Lennart and Ojeda, Pedro and Wollmer, Per},
  issn         = {1473-4877},
  keyword      = {Allergy,Microemulsion,Treatment},
  language     = {eng},
  number       = {6},
  pages        = {1131--1137},
  publisher    = {LibraPharm},
  series       = {Current Medical Research and Opinion},
  title        = {Barrier-enforcing measures as treatment principle in allergic rhinitis: a systematic review},
  url          = {http://dx.doi.org/10.1185/03007995.2014.882299},
  volume       = {30},
  year         = {2014},
}