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A long-term follow-up of clinical response and regional cerebral blood flow changes in depressed patients treated with ECT.

Berggren, Ake; Gustafson, Lars LU ; Höglund, Peter LU and Johanson, Aki LU (2014) In Journal of Affective Disorders 167(Jun 12). p.235-243
Abstract
Depression is the leading cause of disability worldwide and electroconvulsive therapy (ECT) is the most potent therapy. We investigated the clinical response and regional cerebral blood flow changes in depressed in patients treated with (ECT) in a repeated longitudinal study. Method: Forty-nine patients (21 men and 28 women) with a mean age 61 years underwent ECT. Forty-one patients grading improvement after the initial ECT-series (responder group) were compared with eight, grading no improvement (non-responder group). The patients underwent neuropsychiatric ratings, measure of clinical response (defined as≥50% reduction of pre-treatment depression score) and measure of regional cerebral blood flow (rCBF).
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Affective Disorders
volume
167
issue
Jun 12
pages
235 - 243
publisher
Elsevier
external identifiers
  • pmid:24997226
  • wos:000341335700037
  • scopus:84903850359
ISSN
1573-2517
DOI
10.1016/j.jad.2014.06.005
language
English
LU publication?
yes
id
52f292cc-16b9-41a5-8fa8-599e6a1db539 (old id 4583386)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24997226?dopt=Abstract
date added to LUP
2014-08-07 00:27:05
date last changed
2017-08-27 03:06:22
@article{52f292cc-16b9-41a5-8fa8-599e6a1db539,
  abstract     = {Depression is the leading cause of disability worldwide and electroconvulsive therapy (ECT) is the most potent therapy. We investigated the clinical response and regional cerebral blood flow changes in depressed in patients treated with (ECT) in a repeated longitudinal study. Method: Forty-nine patients (21 men and 28 women) with a mean age 61 years underwent ECT. Forty-one patients grading improvement after the initial ECT-series (responder group) were compared with eight, grading no improvement (non-responder group). The patients underwent neuropsychiatric ratings, measure of clinical response (defined as≥50% reduction of pre-treatment depression score) and measure of regional cerebral blood flow (rCBF).},
  author       = {Berggren, Ake and Gustafson, Lars and Höglund, Peter and Johanson, Aki},
  issn         = {1573-2517},
  language     = {eng},
  number       = {Jun 12},
  pages        = {235--243},
  publisher    = {Elsevier},
  series       = {Journal of Affective Disorders},
  title        = {A long-term follow-up of clinical response and regional cerebral blood flow changes in depressed patients treated with ECT.},
  url          = {http://dx.doi.org/10.1016/j.jad.2014.06.005},
  volume       = {167},
  year         = {2014},
}