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Body composition, dietary protein and body weight regulation. Reconciling conflicting results from intervention and observational studies?

Ankarfeldt, Mikkel Z; Angquist, Lars; Stocks, Tanja LU ; Jakobsen, Marianne U; Overvad, Kim; Halkjær, Jytte; Saris, Wim H M; Astrup, Arne and Sørensen, Thorkild I A (2014) In PLoS ONE 9(7).
Abstract
Physiological evidence indicates that high-protein diets reduce caloric intake and increase thermogenic response, which may prevent weight gain and regain after weight loss. Clinical trials have shown such effects, whereas observational cohort studies suggest an association between greater protein intake and weight gain. In both types of studies the results are based on average weight changes, and show considerable diversity in both directions. This study investigates whether the discrepancy in the evidence could be due to recruitment of overweight and obese individuals into clinical trials.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
9
issue
7
publisher
Public Library of Science
external identifiers
  • pmid:24992329
  • wos:000341253400045
  • scopus:84903794351
ISSN
1932-6203
DOI
10.1371/journal.pone.0101134
language
English
LU publication?
yes
id
9c44aadb-fd18-4063-8213-eca6b62a6e46 (old id 4583579)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24992329?dopt=Abstract
date added to LUP
2014-08-06 23:37:48
date last changed
2017-07-09 04:12:37
@article{9c44aadb-fd18-4063-8213-eca6b62a6e46,
  abstract     = {Physiological evidence indicates that high-protein diets reduce caloric intake and increase thermogenic response, which may prevent weight gain and regain after weight loss. Clinical trials have shown such effects, whereas observational cohort studies suggest an association between greater protein intake and weight gain. In both types of studies the results are based on average weight changes, and show considerable diversity in both directions. This study investigates whether the discrepancy in the evidence could be due to recruitment of overweight and obese individuals into clinical trials.},
  articleno    = {e101134},
  author       = {Ankarfeldt, Mikkel Z and Angquist, Lars and Stocks, Tanja and Jakobsen, Marianne U and Overvad, Kim and Halkjær, Jytte and Saris, Wim H M and Astrup, Arne and Sørensen, Thorkild I A},
  issn         = {1932-6203},
  language     = {eng},
  number       = {7},
  publisher    = {Public Library of Science},
  series       = {PLoS ONE},
  title        = {Body composition, dietary protein and body weight regulation. Reconciling conflicting results from intervention and observational studies?},
  url          = {http://dx.doi.org/10.1371/journal.pone.0101134},
  volume       = {9},
  year         = {2014},
}