Advanced

Composite Material Based on Macroporous Polyaniline and Osmium Redox Complex for Biosensor Development

Antiochia, Riccarda; Mazzei, Franco; Gorton, Lo LU ; Leech, Donal and Favero, Gabriele (2014) In Electroanalysis 26(7). p.1623-1630
Abstract
Here the feasibility of layers based on the conducting polymer polyaniline (PANI) as component of glucose biosensors using glucose oxidase (GOx) as enzyme and [Os(bpy)(2)(4-aminomethylpyridine)Cl]PF6 (OsCmplx) as electrochemical mediator, is evaluated. Particularly, PANI was employed to obtain a nanostructured macroporous material (m-PANI) around polystyrene nanoparticles taken as template and the mediator was co-immobilized during the polymerizing procedure. The GOx biosensor based on OsCmplx modified m-PANI provides a linear response to glucose concentration in the range 5 up to 65 mM with a sensitivity of 3.54 mu A/mM/cm(2) (on a projected geometric area=0.07 cm(2)), an LOD of 0.8 mM and a good precision (%RSD <= 7, n=5); the... (More)
Here the feasibility of layers based on the conducting polymer polyaniline (PANI) as component of glucose biosensors using glucose oxidase (GOx) as enzyme and [Os(bpy)(2)(4-aminomethylpyridine)Cl]PF6 (OsCmplx) as electrochemical mediator, is evaluated. Particularly, PANI was employed to obtain a nanostructured macroporous material (m-PANI) around polystyrene nanoparticles taken as template and the mediator was co-immobilized during the polymerizing procedure. The GOx biosensor based on OsCmplx modified m-PANI provides a linear response to glucose concentration in the range 5 up to 65 mM with a sensitivity of 3.54 mu A/mM/cm(2) (on a projected geometric area=0.07 cm(2)), an LOD of 0.8 mM and a good precision (%RSD <= 7, n=5); the biosensor is stable showing a decrease of 10% to the value of the sensitivity after 15 days of use and of about 50% after 40 days. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Polyaniline, Macroporous material, Osmium redox complex, Glucose, biosensor
in
Electroanalysis
volume
26
issue
7
pages
1623 - 1630
publisher
John Wiley & Sons
external identifiers
  • wos:000339483200024
  • scopus:84904071488
ISSN
1040-0397
DOI
10.1002/elan.201400021
language
English
LU publication?
yes
id
65723311-7b7d-4ad7-a874-ec4d604c4b5e (old id 4590737)
date added to LUP
2014-09-04 11:30:33
date last changed
2017-04-09 04:06:02
@article{65723311-7b7d-4ad7-a874-ec4d604c4b5e,
  abstract     = {Here the feasibility of layers based on the conducting polymer polyaniline (PANI) as component of glucose biosensors using glucose oxidase (GOx) as enzyme and [Os(bpy)(2)(4-aminomethylpyridine)Cl]PF6 (OsCmplx) as electrochemical mediator, is evaluated. Particularly, PANI was employed to obtain a nanostructured macroporous material (m-PANI) around polystyrene nanoparticles taken as template and the mediator was co-immobilized during the polymerizing procedure. The GOx biosensor based on OsCmplx modified m-PANI provides a linear response to glucose concentration in the range 5 up to 65 mM with a sensitivity of 3.54 mu A/mM/cm(2) (on a projected geometric area=0.07 cm(2)), an LOD of 0.8 mM and a good precision (%RSD &lt;= 7, n=5); the biosensor is stable showing a decrease of 10% to the value of the sensitivity after 15 days of use and of about 50% after 40 days.},
  author       = {Antiochia, Riccarda and Mazzei, Franco and Gorton, Lo and Leech, Donal and Favero, Gabriele},
  issn         = {1040-0397},
  keyword      = {Polyaniline,Macroporous material,Osmium redox complex,Glucose,biosensor},
  language     = {eng},
  number       = {7},
  pages        = {1623--1630},
  publisher    = {John Wiley & Sons},
  series       = {Electroanalysis},
  title        = {Composite Material Based on Macroporous Polyaniline and Osmium Redox Complex for Biosensor Development},
  url          = {http://dx.doi.org/10.1002/elan.201400021},
  volume       = {26},
  year         = {2014},
}