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Automatic individualized contrast medium dosage during hepatic computed tomography by using computed tomography dose index volume (CTDIvol)

Svensson, Anders ; Björk, Jonas LU ; Cederlund, Kerstin ; Aspelin, Peter ; Nyman, Ulf and Brismar, Torkel B. (2014) In European Radiology 24(8). p.1959-1963
Abstract
To compare hepatic parenchymal contrast media (CM) enhancement during multi-detector row computed tomography (MDCT) and its correlation with volume pitch-corrected computed tomography dose index CTDIvol) and body weight (BW). One hundred patients referred for standard three-phase thoraco-abdominal MDCT examination were enrolled. BW was measured in the CT suite. Forty grams of iodine was administered intravenously (iodixanol 320 mg I/ml at 5 ml/s or iomeprol 400 mg I/ml at 4 ml/s) followed by a 50-ml saline flush. CTDIvol presented by the CT equipment during the parenchymal examination was recorded. The CM enhancement of the liver was defined as the attenuation HU of the liver parenchyma during the hepatic parenchymal phase minus the... (More)
To compare hepatic parenchymal contrast media (CM) enhancement during multi-detector row computed tomography (MDCT) and its correlation with volume pitch-corrected computed tomography dose index CTDIvol) and body weight (BW). One hundred patients referred for standard three-phase thoraco-abdominal MDCT examination were enrolled. BW was measured in the CT suite. Forty grams of iodine was administered intravenously (iodixanol 320 mg I/ml at 5 ml/s or iomeprol 400 mg I/ml at 4 ml/s) followed by a 50-ml saline flush. CTDIvol presented by the CT equipment during the parenchymal examination was recorded. The CM enhancement of the liver was defined as the attenuation HU of the liver parenchyma during the hepatic parenchymal phase minus the attenuation in the native phase. Liver parenchymal enhancement was negatively correlated to both CTDIvol (r = -0.60) and BW (r = -0.64), but the difference in correlation between those two was not significant. CTDIvol may replace BW when adjusting CM doses to body size. This makes it potentially feasible to automatically individualize CM dosage by CT. aEuro cent CTDI (vol) is related to liver CM enhancement in the parenchymal phase. aEuro cent CTDI (vol) provides comparable information to body weight (BW). aEuro cent CTDI (vol) may be used when automatically adjusting CM dose for patient size. (Less)
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Computed tomography, Contrast media, Injection protocol, Radiation dose
in
European Radiology
volume
24
issue
8
pages
1959 - 1963
publisher
Springer
external identifiers
  • wos:000339271800029
  • scopus:84905565311
  • pmid:24859598
ISSN
0938-7994
DOI
10.1007/s00330-014-3220-z
language
English
LU publication?
yes
id
bc56a8e5-0abe-4cbb-a0d8-fa06959abaeb (old id 4591838)
date added to LUP
2016-04-01 11:05:40
date last changed
2022-02-10 08:42:22
@article{bc56a8e5-0abe-4cbb-a0d8-fa06959abaeb,
  abstract     = {{To compare hepatic parenchymal contrast media (CM) enhancement during multi-detector row computed tomography (MDCT) and its correlation with volume pitch-corrected computed tomography dose index CTDIvol) and body weight (BW). One hundred patients referred for standard three-phase thoraco-abdominal MDCT examination were enrolled. BW was measured in the CT suite. Forty grams of iodine was administered intravenously (iodixanol 320 mg I/ml at 5 ml/s or iomeprol 400 mg I/ml at 4 ml/s) followed by a 50-ml saline flush. CTDIvol presented by the CT equipment during the parenchymal examination was recorded. The CM enhancement of the liver was defined as the attenuation HU of the liver parenchyma during the hepatic parenchymal phase minus the attenuation in the native phase. Liver parenchymal enhancement was negatively correlated to both CTDIvol (r = -0.60) and BW (r = -0.64), but the difference in correlation between those two was not significant. CTDIvol may replace BW when adjusting CM doses to body size. This makes it potentially feasible to automatically individualize CM dosage by CT. aEuro cent CTDI (vol) is related to liver CM enhancement in the parenchymal phase. aEuro cent CTDI (vol) provides comparable information to body weight (BW). aEuro cent CTDI (vol) may be used when automatically adjusting CM dose for patient size.}},
  author       = {{Svensson, Anders and Björk, Jonas and Cederlund, Kerstin and Aspelin, Peter and Nyman, Ulf and Brismar, Torkel B.}},
  issn         = {{0938-7994}},
  keywords     = {{Computed tomography; Contrast media; Injection protocol; Radiation dose}},
  language     = {{eng}},
  number       = {{8}},
  pages        = {{1959--1963}},
  publisher    = {{Springer}},
  series       = {{European Radiology}},
  title        = {{Automatic individualized contrast medium dosage during hepatic computed tomography by using computed tomography dose index volume (CTDIvol)}},
  url          = {{http://dx.doi.org/10.1007/s00330-014-3220-z}},
  doi          = {{10.1007/s00330-014-3220-z}},
  volume       = {{24}},
  year         = {{2014}},
}