Life-Space Mobility in Parkinson’s Disease: Associations with Motor and Non-Motor Symptoms
Rantakokko, Merja ; Iwarsson, Susanne LU ; Slaug, Björn LU
and Nilsson, Maria H
LU
(2019)
In Journals of Gerontology. Series A: Biological Sciences & Medical Sciences
74(4).
p.507-512
- Abstract
- Background: To describe life-space mobility and explore associations of motor and non-motor symptoms with life-space mobility in people with Parkinson’s disease (PD).
Methods: About 164 community-dwelling persons with PD (mean age 71.6 years, 64.6% men) received a postal survey and a subsequent home visit. Motor assessments included perceived walking difficulties (Walk-12G), mobility (Timed Up and Go test), motor symptoms (UPDRS-III), and freezing of gait (item 3, FOG-Qsa). Non-motor symptoms included depressive symptoms (GDS-15), pain, fatigue (NHP-EN), and global cognition (MoCA). Life-space mobility was assessed with the life-space assessment (LSA). Calculations included composite score (range 0–120; higher indicating better... (More) - Background: To describe life-space mobility and explore associations of motor and non-motor symptoms with life-space mobility in people with Parkinson’s disease (PD).
Methods: About 164 community-dwelling persons with PD (mean age 71.6 years, 64.6% men) received a postal survey and a subsequent home visit. Motor assessments included perceived walking difficulties (Walk-12G), mobility (Timed Up and Go test), motor symptoms (UPDRS-III), and freezing of gait (item 3, FOG-Qsa). Non-motor symptoms included depressive symptoms (GDS-15), pain, fatigue (NHP-EN), and global cognition (MoCA). Life-space mobility was assessed with the life-space assessment (LSA). Calculations included composite score (range 0–120; higher indicating better life-space mobility), independent life-space (range 0–5), assisted life-space (range 0–5), and maximal life-space (range
0–5). Associations were analyzed with linear regression models, adjusted for age, sex, and PD severity (Hoehn and Yahr).
Results: Mean life-space mobility score was 72.3 (SD = 28.8). Almost all participants (90%) reached the highest life-space level (beyond town). Half of these reached this level independently, while one-third were unable to move outside their bedroom without assistive devices or personal help. When adjusted for confounders, depressive symptoms, pain, and perceived walking difficulties was negatively associated with life-space mobility. In the multivariable model, only perceived walking difficulties were associated with life-space mobility.
Conclusions: Our findings indicate that perceived walking difficulties should be targeted to maintain or improve life-space mobility in people with PD. Depressive symptoms and pain may also merit consideration. More research is needed to elucidate the role of environmental and personal factors for life-space mobility in PD. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/45afde64-fa07-461e-bb43-a5553a55f039
- author
- Rantakokko, Merja
; Iwarsson, Susanne
LU
; Slaug, Björn
LU
and Nilsson, Maria H
LU
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journals of Gerontology. Series A: Biological Sciences & Medical Sciences
- volume
- 74
- issue
- 4
- pages
- 6 pages
- publisher
- Oxford University Press
- external identifiers
-
- scopus:85062953604
- pmid:29648576
- ISSN
- 1758-535X
- DOI
- 10.1093/gerona/gly074
- project
- Home and health in people ageing with Parkinson's disease
- Home, Health and Disability along the Process of Ageing
- language
- English
- LU publication?
- yes
- id
- 45afde64-fa07-461e-bb43-a5553a55f039
- date added to LUP
- 2018-12-05 10:59:31
- date last changed
- 2022-05-11 03:38:31
@article{45afde64-fa07-461e-bb43-a5553a55f039,
abstract = {{Background: To describe life-space mobility and explore associations of motor and non-motor symptoms with life-space mobility in people with Parkinson’s disease (PD).<br/>Methods: About 164 community-dwelling persons with PD (mean age 71.6 years, 64.6% men) received a postal survey and a subsequent home visit. Motor assessments included perceived walking difficulties (Walk-12G), mobility (Timed Up and Go test), motor symptoms (UPDRS-III), and freezing of gait (item 3, FOG-Qsa). Non-motor symptoms included depressive symptoms (GDS-15), pain, fatigue (NHP-EN), and global cognition (MoCA). Life-space mobility was assessed with the life-space assessment (LSA). Calculations included composite score (range 0–120; higher indicating better life-space mobility), independent life-space (range 0–5), assisted life-space (range 0–5), and maximal life-space (range<br/>0–5). Associations were analyzed with linear regression models, adjusted for age, sex, and PD severity (Hoehn and Yahr).<br/>Results: Mean life-space mobility score was 72.3 (SD = 28.8). Almost all participants (90%) reached the highest life-space level (beyond town). Half of these reached this level independently, while one-third were unable to move outside their bedroom without assistive devices or personal help. When adjusted for confounders, depressive symptoms, pain, and perceived walking difficulties was negatively associated with life-space mobility. In the multivariable model, only perceived walking difficulties were associated with life-space mobility.<br/>Conclusions: Our findings indicate that perceived walking difficulties should be targeted to maintain or improve life-space mobility in people with PD. Depressive symptoms and pain may also merit consideration. More research is needed to elucidate the role of environmental and personal factors for life-space mobility in PD.}},
author = {{Rantakokko, Merja and Iwarsson, Susanne and Slaug, Björn and Nilsson, Maria H}},
issn = {{1758-535X}},
language = {{eng}},
number = {{4}},
pages = {{507--512}},
publisher = {{Oxford University Press}},
series = {{Journals of Gerontology. Series A: Biological Sciences & Medical Sciences}},
title = {{Life-Space Mobility in Parkinson’s Disease: Associations with Motor and Non-Motor Symptoms}},
url = {{http://dx.doi.org/10.1093/gerona/gly074}},
doi = {{10.1093/gerona/gly074}},
volume = {{74}},
year = {{2019}},
}