Multiple Associated Variants Increase the Heritability Explained for Plasma Lipids and Coronary Artery Disease.
(2014) In Circulation: Cardiovascular Genetics 7(5). p.583-587- Abstract
- -Plasma lipid levels as well as coronary artery disease (CAD) have been shown to be highly heritable with estimates ranging from 40%-60%. However, top variants detected by large-scale genome-wide association studies (GWAS) explain only a fraction of the total variance in plasma lipid phenotypes and CAD.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4612723
- author
- Tada, Hayato
; Won, Hong-Hee
; Melander, Olle
LU
; Yang, Jian ; Peloso, Gina M and Kathiresan, Sekar
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Circulation: Cardiovascular Genetics
- volume
- 7
- issue
- 5
- pages
- 583 - 587
- publisher
- American Heart Association
- external identifiers
-
- pmid:25170055
- wos:000344368200004
- scopus:84925860386
- pmid:25170055
- ISSN
- 1942-325X
- DOI
- 10.1161/CIRCGENETICS.113.000420
- language
- English
- LU publication?
- yes
- id
- 39bcce0e-2616-4d74-b1f3-c7e157187d43 (old id 4612723)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25170055?dopt=Abstract
- date added to LUP
- 2016-04-01 10:21:07
- date last changed
- 2024-01-06 14:29:07
@article{39bcce0e-2616-4d74-b1f3-c7e157187d43, abstract = {{-Plasma lipid levels as well as coronary artery disease (CAD) have been shown to be highly heritable with estimates ranging from 40%-60%. However, top variants detected by large-scale genome-wide association studies (GWAS) explain only a fraction of the total variance in plasma lipid phenotypes and CAD.}}, author = {{Tada, Hayato and Won, Hong-Hee and Melander, Olle and Yang, Jian and Peloso, Gina M and Kathiresan, Sekar}}, issn = {{1942-325X}}, language = {{eng}}, number = {{5}}, pages = {{583--587}}, publisher = {{American Heart Association}}, series = {{Circulation: Cardiovascular Genetics}}, title = {{Multiple Associated Variants Increase the Heritability Explained for Plasma Lipids and Coronary Artery Disease.}}, url = {{http://dx.doi.org/10.1161/CIRCGENETICS.113.000420}}, doi = {{10.1161/CIRCGENETICS.113.000420}}, volume = {{7}}, year = {{2014}}, }