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Prediction of hypotension in hemodialysis patients

Sandberg, Frida LU ; Bailón, Raquel; Hernando, David; Laguna, Pablo; Martínez, Juan Pablo; Solem, Kristian and Sörnmo, Leif LU (2014) In Physiological Measurement 35(9). p.1885-1898
Abstract
Intradialytic hypotension (IDH) is the most common adverse complication during hemodialysis. Its early prediction and prevention will dramatically improve the quality of life for patients with an end stage renal disease. In a recent study, changes in the normalized envelope of the test statistic of the photoplethysmograpic (PPG) signal were found to predict acute symptomatic IDH. In the present study, the PPG-based predictor is generalized to include a patient-dependent threshold which incorporates on-line information on heart rate variability and heart rate turbulence. From datasets with patients prone and resistant to IDH, the results show that symptomatic IDH could be correctly predicted in 9 out of 14 cases, while 5 out of 24 were... (More)
Intradialytic hypotension (IDH) is the most common adverse complication during hemodialysis. Its early prediction and prevention will dramatically improve the quality of life for patients with an end stage renal disease. In a recent study, changes in the normalized envelope of the test statistic of the photoplethysmograpic (PPG) signal were found to predict acute symptomatic IDH. In the present study, the PPG-based predictor is generalized to include a patient-dependent threshold which incorporates on-line information on heart rate variability and heart rate turbulence. From datasets with patients prone and resistant to IDH, the results show that symptomatic IDH could be correctly predicted in 9 out of 14 cases, while 5 out of 24 were falsely predicted. In a subset of the data containing only patients prone to IDH, acute symptomatic IDH could be correctly predicted in 5 out of 5 cases, with one false prediction out of 14. When testing the robustness of the predictor, no significant changes were observed in the test statistic when controlled changes occurred in dialysis fluid temperature, ultrafiltration rate and body position. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Physiological Measurement
volume
35
issue
9
pages
1885 - 1898
publisher
IOP Publishing
external identifiers
  • pmid:25154735
  • wos:000343765700013
  • scopus:84906727674
ISSN
0967-3334
DOI
10.1088/0967-3334/35/9/1885
language
English
LU publication?
yes
id
a8857493-2caa-4587-aa4f-8e94c619eda0 (old id 4618774)
date added to LUP
2014-09-10 15:48:22
date last changed
2017-01-01 04:02:26
@article{a8857493-2caa-4587-aa4f-8e94c619eda0,
  abstract     = {Intradialytic hypotension (IDH) is the most common adverse complication during hemodialysis. Its early prediction and prevention will dramatically improve the quality of life for patients with an end stage renal disease. In a recent study, changes in the normalized envelope of the test statistic of the photoplethysmograpic (PPG) signal were found to predict acute symptomatic IDH. In the present study, the PPG-based predictor is generalized to include a patient-dependent threshold which incorporates on-line information on heart rate variability and heart rate turbulence. From datasets with patients prone and resistant to IDH, the results show that symptomatic IDH could be correctly predicted in 9 out of 14 cases, while 5 out of 24 were falsely predicted. In a subset of the data containing only patients prone to IDH, acute symptomatic IDH could be correctly predicted in 5 out of 5 cases, with one false prediction out of 14. When testing the robustness of the predictor, no significant changes were observed in the test statistic when controlled changes occurred in dialysis fluid temperature, ultrafiltration rate and body position.},
  author       = {Sandberg, Frida and Bailón, Raquel and Hernando, David and Laguna, Pablo and Martínez, Juan Pablo and Solem, Kristian and Sörnmo, Leif},
  issn         = {0967-3334},
  language     = {eng},
  number       = {9},
  pages        = {1885--1898},
  publisher    = {IOP Publishing},
  series       = {Physiological Measurement},
  title        = {Prediction of hypotension in hemodialysis patients},
  url          = {http://dx.doi.org/10.1088/0967-3334/35/9/1885},
  volume       = {35},
  year         = {2014},
}