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Volume Tracking: A new method for quantitative assessment and visualization of intracardiac blood flow from three-dimensional, time-resolved, three-component magnetic resonance velocity mapping

Töger, Johannes LU ; Carlsson, Marcus LU ; Söderlind, Gustaf LU ; Arheden, Håkan LU and Heiberg, Einar LU (2011) In BMC Medical Imaging 11.
Abstract
Background: Functional and morphological changes of the heart influence blood flow patterns. Therefore, flow patterns may carry diagnostic and prognostic information. Three-dimensional, time-resolved, three-directional phase contrast cardiovascular magnetic resonance (4D PC-CMR) can image flow patterns with unique detail, and using new flow visualization methods may lead to new insights. The aim of this study is to present and validate a novel visualization method with a quantitative potential for blood flow from 4D PC-CMR, called Volume Tracking, and investigate if Volume Tracking complements particle tracing, the most common visualization method used today.

Methods: Eight healthy volunteers and one patient with a large apical... (More)
Background: Functional and morphological changes of the heart influence blood flow patterns. Therefore, flow patterns may carry diagnostic and prognostic information. Three-dimensional, time-resolved, three-directional phase contrast cardiovascular magnetic resonance (4D PC-CMR) can image flow patterns with unique detail, and using new flow visualization methods may lead to new insights. The aim of this study is to present and validate a novel visualization method with a quantitative potential for blood flow from 4D PC-CMR, called Volume Tracking, and investigate if Volume Tracking complements particle tracing, the most common visualization method used today.

Methods: Eight healthy volunteers and one patient with a large apical left ventricular aneurysm underwent 4D PC- CMR flow imaging of the whole heart. Volume Tracking and particle tracing visualizations were compared visually side-by-side in a visualization software package. To validate Volume Tracking, the number of particle traces that agreed with the Volume Tracking visualizations was counted and expressed as a percentage of total released particles in mid-diastole and end-diastole respectively. Two independent observers described blood flow patterns in the left ventricle using Volume Tracking visualizations.

Results: Volume Tracking was feasible in all eight healthy volunteers and in the patient. Visually, Volume Tracking and particle tracing are complementary methods, showing different aspects of the flow. When validated against particle tracing, on average 90.5% and 87.8% of the particles agreed with the Volume Tracking surface in mid- diastole and end-diastole respectively. Inflow patterns in the left ventricle varied between the subjects, with excellent agreement between observers. The left ventricular inflow pattern in the patient differed from the healthy subjects.

Conclusion: Volume Tracking is a new visualization method for blood flow measured by 4D PC-CMR. Volume Tracking complements and provides incremental information compared to particle tracing that may lead to a better understanding of blood flow and may improve diagnosis and prognosis of cardiovascular diseases. (Less)
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organization
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Contribution to journal
publication status
published
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in
BMC Medical Imaging
volume
11
publisher
BioMed Central
external identifiers
  • scopus:79953883564
ISSN
1471-2342
DOI
10.1186/1471-2342-11-10
language
English
LU publication?
yes
id
b40ce648-32c6-4d96-8c3b-9ce6c3e3346c (old id 4647852)
alternative location
http://www.biomedcentral.com/1471-2342/11/10
date added to LUP
2014-10-22 18:43:41
date last changed
2017-11-12 03:45:59
@article{b40ce648-32c6-4d96-8c3b-9ce6c3e3346c,
  abstract     = {Background: Functional and morphological changes of the heart influence blood flow patterns. Therefore, flow patterns may carry diagnostic and prognostic information. Three-dimensional, time-resolved, three-directional phase contrast cardiovascular magnetic resonance (4D PC-CMR) can image flow patterns with unique detail, and using new flow visualization methods may lead to new insights. The aim of this study is to present and validate a novel visualization method with a quantitative potential for blood flow from 4D PC-CMR, called Volume Tracking, and investigate if Volume Tracking complements particle tracing, the most common visualization method used today.<br/><br>
Methods: Eight healthy volunteers and one patient with a large apical left ventricular aneurysm underwent 4D PC- CMR flow imaging of the whole heart. Volume Tracking and particle tracing visualizations were compared visually side-by-side in a visualization software package. To validate Volume Tracking, the number of particle traces that agreed with the Volume Tracking visualizations was counted and expressed as a percentage of total released particles in mid-diastole and end-diastole respectively. Two independent observers described blood flow patterns in the left ventricle using Volume Tracking visualizations.<br/><br>
Results: Volume Tracking was feasible in all eight healthy volunteers and in the patient. Visually, Volume Tracking and particle tracing are complementary methods, showing different aspects of the flow. When validated against particle tracing, on average 90.5% and 87.8% of the particles agreed with the Volume Tracking surface in mid- diastole and end-diastole respectively. Inflow patterns in the left ventricle varied between the subjects, with excellent agreement between observers. The left ventricular inflow pattern in the patient differed from the healthy subjects.<br/><br>
Conclusion: Volume Tracking is a new visualization method for blood flow measured by 4D PC-CMR. Volume Tracking complements and provides incremental information compared to particle tracing that may lead to a better understanding of blood flow and may improve diagnosis and prognosis of cardiovascular diseases.},
  author       = {Töger, Johannes and Carlsson, Marcus and Söderlind, Gustaf and Arheden, Håkan and Heiberg, Einar},
  issn         = {1471-2342},
  language     = {eng},
  publisher    = {BioMed Central},
  series       = {BMC Medical Imaging},
  title        = {Volume Tracking: A new method for quantitative assessment and visualization of intracardiac blood flow from three-dimensional, time-resolved, three-component magnetic resonance velocity mapping},
  url          = {http://dx.doi.org/10.1186/1471-2342-11-10},
  volume       = {11},
  year         = {2011},
}