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ATRIOVENTRICULAR CONDUCTION in Patients with Paroxysmal Supraventricular Tachycardias

Liu, Shaowen LU (2003)
Abstract
This thesis concerns retrospective and prospective studies of the atrioventricular (AV) conduction properties in patients with cardiac arrhythmias. The objectives of the retrospective studies were to further delineate the sex distribution in patients with Wolff-Parkinson-White syndrome (WPW) and AV nodal reentrant tachycardia (AVNRT) and to determine the underlying mechanisms of the differences in sex distribution, to investigate the relationship between the conduction properties of normal and accessory AV pathway, and to evaluate their conduction properties with respect to accessory pathway location. AV nodal characteristics were studied in 328 patients with AVNRT, 356 with manifest and 220 with concealed WPW who underwent radiofrequency... (More)
This thesis concerns retrospective and prospective studies of the atrioventricular (AV) conduction properties in patients with cardiac arrhythmias. The objectives of the retrospective studies were to further delineate the sex distribution in patients with Wolff-Parkinson-White syndrome (WPW) and AV nodal reentrant tachycardia (AVNRT) and to determine the underlying mechanisms of the differences in sex distribution, to investigate the relationship between the conduction properties of normal and accessory AV pathway, and to evaluate their conduction properties with respect to accessory pathway location. AV nodal characteristics were studied in 328 patients with AVNRT, 356 with manifest and 220 with concealed WPW who underwent radiofrequency ablation and compared to 146 controls. It was concluded that a relatively long AV conduction time is an electrophysiological prerequisite for the manifestation of ventricular preexcitation. The anterograde conduction capability of the normal and accessory AV pathway is associated with specific accessory pathway location. Differences in sex distribution exist among patients with manifest and concealed WPW and AVNRT, and it may be attributed to the gender differences in AV conduction and AV conduction properties required for the manifestation of preexcitation and induction of AVNRT. The interaction of AV nodal concealment and duality was prospectively studied in 20 patients with AVNRT and 14 controls. By comparing the properties of AV conduction curves in the presence and absence of a blocked atrial impulse between patients with and without AVNRT, before and after slow pathway ablation, we concluded that the concealed conduction of AV node has substantial effects on succeeding conduction. The magnitude of concealment is independent of the presence or absence of slow pathway conduction. (Less)
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author
supervisor
opponent
  • Professor Bergfeldt, Lennart, Stockholm
organization
publishing date
type
Thesis
publication status
published
subject
keywords
Cardiovascular system, Kardiovaskulära systemet
pages
162 pages
publisher
Shaowen Liu, Dept Cardiology, University Hospital, Lund, Sweden,
defense location
Segerfalkssalen, BMC, Lund
defense date
2003-05-22 10:15:00
ISBN
91-628-5636-7
language
English
LU publication?
yes
additional info
Article: I. Shaowen Liu, Shiwen Yuan, Eva Hertervig, Ole Kongstad, S. Bertil Olsson. Gender and Atrioventricular Conduction Properties of Patients with Symptomatic Atrioventricular Nodal Reentrant Tachycardia and Wolff-Parkinson-White Syndrome. J Electrocardiology. 2001,34(4): 295-301. Article: II. Shaowen Liu, S. Olsson Bertil, Eva Hertervig, Ole Kongstad, Shiwen Yuan. Atrioventricular Conduction: A Determinant for the Manifestation of Ventricular Preexcitation in Patients with Wolff-Parkinson-White Syndrome. Clinical Physiology. 2001,21(5):534-540. Article: III. Shaowen Liu, Shiwen Yuan, Ole Kongstad, S. Bertil Olsson. Gender differences in the electrophysiological characteristics of atrioventricular conduction system and their clinical implications. Scand Cardiovasc J. 2001,35(5):313-317. Article: IV. Shaowen Liu, Shiwen Yuan, S. Bertil Olsson. Conduction Properties of Accessory Atrioventricular Pathways: Importance of the Accessory Pathway Location and Normal Atrioventricular Conduction. Scand Cardiovasc J. In press. Article: V. Shaowen Liu, Shiwen Yuan, Yanzong Yang, Eva Hertervig, Ole Kongstad, S. Bertil Olsson. Concealed conduction and dual pathway physiology of atrioventricular node. In manuscript.
id
2b1b1792-5104-4461-b43c-e9ee124b8ecf (old id 465676)
date added to LUP
2016-04-04 11:48:29
date last changed
2018-11-21 21:07:21
@phdthesis{2b1b1792-5104-4461-b43c-e9ee124b8ecf,
  abstract     = {This thesis concerns retrospective and prospective studies of the atrioventricular (AV) conduction properties in patients with cardiac arrhythmias. The objectives of the retrospective studies were to further delineate the sex distribution in patients with Wolff-Parkinson-White syndrome (WPW) and AV nodal reentrant tachycardia (AVNRT) and to determine the underlying mechanisms of the differences in sex distribution, to investigate the relationship between the conduction properties of normal and accessory AV pathway, and to evaluate their conduction properties with respect to accessory pathway location. AV nodal characteristics were studied in 328 patients with AVNRT, 356 with manifest and 220 with concealed WPW who underwent radiofrequency ablation and compared to 146 controls. It was concluded that a relatively long AV conduction time is an electrophysiological prerequisite for the manifestation of ventricular preexcitation. The anterograde conduction capability of the normal and accessory AV pathway is associated with specific accessory pathway location. Differences in sex distribution exist among patients with manifest and concealed WPW and AVNRT, and it may be attributed to the gender differences in AV conduction and AV conduction properties required for the manifestation of preexcitation and induction of AVNRT. The interaction of AV nodal concealment and duality was prospectively studied in 20 patients with AVNRT and 14 controls. By comparing the properties of AV conduction curves in the presence and absence of a blocked atrial impulse between patients with and without AVNRT, before and after slow pathway ablation, we concluded that the concealed conduction of AV node has substantial effects on succeeding conduction. The magnitude of concealment is independent of the presence or absence of slow pathway conduction.},
  author       = {Liu, Shaowen},
  isbn         = {91-628-5636-7},
  language     = {eng},
  publisher    = {Shaowen Liu, Dept Cardiology, University Hospital, Lund, Sweden,},
  school       = {Lund University},
  title        = {ATRIOVENTRICULAR CONDUCTION in Patients with Paroxysmal Supraventricular Tachycardias},
  year         = {2003},
}