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Loud Noise Exposure and Acoustic Neuroma

Fisher, James L.; Pettersson, David; Palmisano, Sadie; Schwartzbaum, Judith A.; Edwards, Colin G.; Mathiesen, Tiit; Prochazka, Michaela; Bergenheim, Tommy; Florentzson, Rut and Harder, Henrik, et al. (2014) In American Journal of Epidemiology 180(1). p.58-67
Abstract
The results from studies of loud noise exposure and acoustic neuroma are conflicting. A population-based case-control study of 451 acoustic neuroma patients and 710 age-, sex-, and region-matched controls was conducted in Sweden between 2002 and 2007. Occupational exposure was based on historical measurements of occupational noise (321 job titles summarized by a job exposure matrix) and compared with self-reported occupational noise exposure. We also evaluated self-reported noise exposure during leisure activity. Conditional logistic regression was used to estimate odds ratios. There was no statistically significant association between acoustic neuroma and persistent occupational noise exposure, either with or without hearing protection.... (More)
The results from studies of loud noise exposure and acoustic neuroma are conflicting. A population-based case-control study of 451 acoustic neuroma patients and 710 age-, sex-, and region-matched controls was conducted in Sweden between 2002 and 2007. Occupational exposure was based on historical measurements of occupational noise (321 job titles summarized by a job exposure matrix) and compared with self-reported occupational noise exposure. We also evaluated self-reported noise exposure during leisure activity. Conditional logistic regression was used to estimate odds ratios. There was no statistically significant association between acoustic neuroma and persistent occupational noise exposure, either with or without hearing protection. Exposure to loud noise from leisure activity without hearing protection was more common among acoustic neuroma cases (odds ratio = 1.47, 95% confidence interval: 1.06, 2.03). Statistically significant odds ratios were found for specific leisure activities including attending concerts/clubs/sporting events (odds ratio = 1.82, 95% confidence interval: 1.09, 3.04) and participating in workouts accompanied by loud music (odds ratio = 2.84, 95% confidence interval: 1.37, 5.89). Our findings do not support an association between occupational exposure to loud noise and acoustic neuroma. Although we report statistically significant associations between leisure-time exposures to loud noise without hearing protection and acoustic neuroma, especially among women, we cannot rule out recall bias as an alternative explanation. (Less)
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Contribution to journal
publication status
published
subject
keywords
acoustic neuroma, noise, occupation, vestibular schwannoma
in
American Journal of Epidemiology
volume
180
issue
1
pages
58 - 67
publisher
Oxford University Press
external identifiers
  • wos:000339808200009
  • scopus:84903937859
ISSN
0002-9262
DOI
10.1093/aje/kwu081
language
English
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yes
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ea744bad-554c-4eb2-8c7c-a1cdc92f28a7 (old id 4667859)
date added to LUP
2014-10-01 07:24:24
date last changed
2017-10-22 03:13:54
@article{ea744bad-554c-4eb2-8c7c-a1cdc92f28a7,
  abstract     = {The results from studies of loud noise exposure and acoustic neuroma are conflicting. A population-based case-control study of 451 acoustic neuroma patients and 710 age-, sex-, and region-matched controls was conducted in Sweden between 2002 and 2007. Occupational exposure was based on historical measurements of occupational noise (321 job titles summarized by a job exposure matrix) and compared with self-reported occupational noise exposure. We also evaluated self-reported noise exposure during leisure activity. Conditional logistic regression was used to estimate odds ratios. There was no statistically significant association between acoustic neuroma and persistent occupational noise exposure, either with or without hearing protection. Exposure to loud noise from leisure activity without hearing protection was more common among acoustic neuroma cases (odds ratio = 1.47, 95% confidence interval: 1.06, 2.03). Statistically significant odds ratios were found for specific leisure activities including attending concerts/clubs/sporting events (odds ratio = 1.82, 95% confidence interval: 1.09, 3.04) and participating in workouts accompanied by loud music (odds ratio = 2.84, 95% confidence interval: 1.37, 5.89). Our findings do not support an association between occupational exposure to loud noise and acoustic neuroma. Although we report statistically significant associations between leisure-time exposures to loud noise without hearing protection and acoustic neuroma, especially among women, we cannot rule out recall bias as an alternative explanation.},
  author       = {Fisher, James L. and Pettersson, David and Palmisano, Sadie and Schwartzbaum, Judith A. and Edwards, Colin G. and Mathiesen, Tiit and Prochazka, Michaela and Bergenheim, Tommy and Florentzson, Rut and Harder, Henrik and Nyberg, Gunnar and Siesjö, Peter and Feychting, Maria},
  issn         = {0002-9262},
  keyword      = {acoustic neuroma,noise,occupation,vestibular schwannoma},
  language     = {eng},
  number       = {1},
  pages        = {58--67},
  publisher    = {Oxford University Press},
  series       = {American Journal of Epidemiology},
  title        = {Loud Noise Exposure and Acoustic Neuroma},
  url          = {http://dx.doi.org/10.1093/aje/kwu081},
  volume       = {180},
  year         = {2014},
}